Inducible endothelial leakiness in nanotherapeutic applications

N Ni, W Wang, Y Sun, X Sun, DT Leong - Biomaterials, 2022 - Elsevier
All intravenous delivered nanomedicine needs to escape from the blood vessel to exert their
therapeutic efficacy at their designated site of action. Failure to do so increases the …

Highlights in ultrasound-targeted microbubble destruction-mediated gene/drug delivery strategy for treatment of malignancies

H Li, Y Zhang, H Shu, W Lv, C Su, F Nie - International Journal of …, 2022 - Elsevier
Ultrasound is one of the safest and most advanced medical imaging technologies that is
widely used in clinical practice. Ultrasound microbubbles, traditionally used for contrast …

State-of-the-art of ultrasound-triggered drug delivery from ultrasound-responsive drug carriers

CH Fan, YJ Ho, CW Lin, N Wu… - Expert Opinion on …, 2022 - Taylor & Francis
Introduction Delivering sufficient therapeutics at the target site without off-target effects is a
major goal of drug delivery technology innovation. Among the established methods …

[HTML][HTML] Exosomes and ultrasound: the future of theranostic applications

B Sridharan, HG Lim - Materials Today Bio, 2023 - Elsevier
Biomaterials and pertaining formulations have been very successful in various diagnostic
and therapeutic applications because of its ability to overcome pharmacological limitations …

Ultrasound-Activatable Phase-Shift Nanoparticle as a Targeting Antibacterial Agent for Efficient Eradication of Pseudomonas aeruginosa Biofilms

L Xin, C Zhang, J Chen, Y Jiang, Y Liu… - … Applied Materials & …, 2022 - ACS Publications
Biofilms are physical barriers composed of extracellular polymeric substances (EPS) that
enable planktonic bacteria to resist host responses and antibacterial treatments …

[HTML][HTML] Advances in BBB on chip and application for studying reversible opening of blood–brain barrier by sonoporation

Y Cai, K Fan, J Lin, L Ma, F Li - Micromachines, 2022 - mdpi.com
The complex structure of the blood–brain barrier (BBB), which blocks nearly all large
biomolecules, hinders drug delivery to the brain and drug assessment, thus decelerating …

Research progress in construction of organic carrier drug delivery platform using tumor microenvironment

H Yan, P Xu, H Cong, B Yu, Y Shen - Materials Today Chemistry, 2024 - Elsevier
At present, chemotherapy is still the main method for treatment of cancer, which can
effectively kill cancer cells and control the metastasis of cancer cells. However, traditional …

[HTML][HTML] Emerging high-frequency ultrasound imaging in medical cosmetology

YP Tao, C Wei, YM Su, B Hu, D Sun - Frontiers in Physiology, 2022 - frontiersin.org
Cosmetic skin diseases are a part of many dermatological concerns brought up by patients,
which negatively affect mental health and quality of life. Imaging technology has an …

In Situ Imaging and Anti-inflammation of 3D Printed Scaffolds enabled by AIEgen

X Wang, P Chen, H Yang, J Liu, R Tu… - … Applied Materials & …, 2023 - ACS Publications
Three-dimensional (3D) printed bioactive scaffolds have been widely used in the field of
bone tissue engineering. However, its in vivo visualization and bacterial inflammation are …

[HTML][HTML] Overcoming Hypoxia-Induced Drug Resistance via Promotion of Drug Uptake and Reoxygenation by Acousto–Mechanical Oxygen Delivery

YJ Ho, DT Thao, CK Yeh - Pharmaceutics, 2022 - mdpi.com
Hypoxia-induced drug resistance (HDR) is a critical issue in cancer therapy. The presence
of hypoxic tumor cells impedes drug uptake and reduces the cytotoxicity of …