Phospholipase C epsilon-1 (PLCƐ1) mediates macrophage activation and protection against tuberculosis

A Gupta, S Thirunavukkarasu… - Infection and …, 2024 - Am Soc Microbiol
Tuberculosis (TB) caused by Mycobacterium tuberculosis (Mtb) infects up to a quarter of the
world's population. Although immune responses can control Mtb infection, 5%–10% of …

Biasing of G-signaling with Small Molecules as a Novel Therapeutic Approach to Improve Opioid-mediated Antinociception

G Sanchez - 2023 - deepblue.lib.umich.edu
Opioid analgesics are widely used as a treatment option for pain management and relief.
However, the misuse of opioid analgesics has contributed to the current opioid epidemic in …