[HTML][HTML] In silico vaccine design: A tutorial in immunoinformatics

DD Martinelli - Healthcare Analytics, 2022 - Elsevier
Immunoinformatics, as a discipline, concerns the application of computational systems to
study the immune system. Recently, the principles of reverse vaccinology have united with …

Plasmodium vivax vaccine: What is the best way to go?

GTS Veiga, MR Moriggi, JF Vettorazzi… - Frontiers in …, 2023 - frontiersin.org
Malaria is one of the most devastating human infectious diseases caused by Plasmodium
spp. parasites. A search for an effective and safe vaccine is the main challenge for its …

Systems biology of malaria explored with nonhuman primates

MR Galinski - Malaria journal, 2022 - Springer
Abstract “The Primate Malarias” book has been a uniquely important resource for multiple
generations of scientists, since its debut in 1971, and remains pertinent to the present day …

A genetically modified Plasmodium berghei parasite as a surrogate for whole-sporozoite vaccination against P. vivax malaria

D Moita, TG Maia, M Duarte, CM Andrade… - npj Vaccines, 2022 - nature.com
Two malaria parasite species, Plasmodium falciparum (Pf) and P. vivax (Pv) are responsible
for most of the disease burden caused by malaria. Vaccine development against this …

Identification of novel Plasmodium vivax proteins associated with protection against clinical malaria

R Mazhari, E Takashima, RJ Longley… - Frontiers in Cellular …, 2023 - frontiersin.org
As progress towards malaria elimination continues, the challenge posed by the parasite
species Plasmodium vivax has become more evident. In many regions co-endemic for P …

Naturally acquired antibody kinetics against Plasmodium vivax antigens in people from a low malaria transmission region in western Thailand

ZSJ Liu, J Sattabongkot, M White, S Chotirat… - BMC medicine, 2022 - Springer
Background Plasmodium vivax (P. vivax) is the dominant Plasmodium spp. causing the
disease malaria in low-transmission regions outside of Africa. These regions often feature …

[HTML][HTML] Review on Cerebral Malaria-Pathogenesis and Role of EphA2 Receptor in Maintaining Blood Brain Barrier Integrity

MS Shaikh, MS Baig, SS Ali, A Ahmad… - Health Sciences …, 2024 - Elsevier
Plasmodium species causes cerebral malaria (CM), a dangerous parasitic illness. The
World Health Organization estimates that there were roughly 228 million cases of malaria in …

Immunogenicity of PvCyRPA, PvCelTOS and Pvs25 chimeric recombinant protein of Plasmodium vivax in murine model

AS Matos, IF Soares, RN Rodrigues-da-Silva… - Frontiers in …, 2024 - frontiersin.org
In the Americas, P. vivax is the predominant causative species of malaria, a debilitating and
economically significant disease. Due to the complexity of the malaria parasite life cycle, a …

A two-dose viral-vectored Plasmodium vivax multistage vaccine confers durable protection and transmission-blockade in a pre-clinical study

Y Yamamoto, C Fabbri, D Okuhara, R Takagi… - Frontiers in …, 2024 - frontiersin.org
Among Plasmodium spp. responsible for human malaria, Plasmodium vivax ranks as the
second most prevalent and has the widest geographical range; however, vaccine …

中缅边境地区间日疟原虫几丁质酶基因的遗传特性分析

张曼, 沈海默, 陈绅波, 陈军虎 - 热带病与寄生虫学, 2024 - rdbzz.com
目的明确中缅边境地区间日疟原虫几丁质酶(Plasmodium vivax chitinase, PvCHT1)
基因的遗传多样性, 探究PvCHT1 基因的地理差异, 为我国间日疟疫苗的设计提供参考 …