Alpha-lipoic acid and glucose metabolism: a comprehensive update on biochemical and therapeutic features

U Capece, S Moffa, I Improta, G Di Giuseppe, EC Nista… - Nutrients, 2022 - mdpi.com
Alpha-lipoic acid (ALA) is a natural compound with antioxidant and pro-oxidant properties
which has effects on the regulation of insulin sensitivity and insulin secretion. ALA is widely …

A systematic review of the therapeutic effects of resveratrol in combination with 5-fluorouracil during colorectal cancer treatment: With a special focus on the oxidant …

H Moutabian, M Majdaeen, R Ghahramani-Asl… - Cancer cell …, 2022 - Springer
Abstract Purpose 5-fluorouracil (5-FU), an effective chemotherapy drug, is commonly
applied for colorectal cancer treatment. Nevertheless, its toxicity to normal tissues and the …

The role of melatonin on doxorubicin-induced cardiotoxicity: a systematic review

M Najafi, MRH Shayesteh, K Mortezaee, B Farhood… - Life sciences, 2020 - Elsevier
Purpose Doxorubicin, as an effective chemotherapeutic drug, is commonly used for
combating various solid and hematological tumors. However, doxorubicin-induced …

A Systematic Review of the Potential Chemoprotective Effects of Resveratrol on Doxorubicin‐Induced Cardiotoxicity: Focus on the Antioxidant, Antiapoptotic, and Anti …

LF Hu, HR Lan, XM Li, KT Jin - Oxidative medicine and cellular …, 2021 - Wiley Online Library
Purpose. Although doxorubicin chemotherapeutic drug is commonly used to treat various
solid and hematological tumors, its clinical use is restricted because of its adverse effects on …

Therapeutic effects of gallic acid in regulating senescence and diabetes; an in vitro study

M Rahimifard, M Baeeri, H Bahadar, S Moini-Nodeh… - Molecules, 2020 - mdpi.com
Gallic acid (GA), a plant-derived ubiquitous secondary polyphenol metabolite, can be a
useful dietary supplement. This in vitro study's primary purpose was to assess the anti-aging …

In vitro and in vivo cardioprotective effects of curcumin against doxorubicin‐induced cardiotoxicity: A systematic review

Q Zhang, L Wu - Journal of oncology, 2022 - Wiley Online Library
Objective. This study aimed to review the potential chemoprotective effects of curcumin
against the doxorubicin‐induced cardiotoxicity. Methods. According to the PRISMA …

Quercetin attenuates pancreatic and renal D-galactose-induced aging-related oxidative alterations in rats

AH El-Far, MA Lebda, AE Noreldin, MS Atta… - International Journal of …, 2020 - mdpi.com
Aging is an oxidative stress-associated process that progresses with age. Our aim is to delay
or attenuate these oxidative alterations and to keep individuals healthy as they age using …

The protective role of melatonin in chemotherapy‐induced nephrotoxicity: a systematic review of non-clinical studies

H Haghi-Aminjan, B Farhood… - Expert opinion on …, 2018 - Taylor & Francis
Introduction: The aim of this study was to investigate the potential role of melatonin in the
prevention of chemotherapy-induced nephrotoxicity at the preclinical level. Areas covered …

Physicochemical characterization of a polysaccharide from Agrocybe aegirita and its anti-ageing activity

X Liu, D Liu, Y Chen, R Zhong, L Gao, C Yang, C Ai… - Carbohydrate …, 2020 - Elsevier
The aim of the present study is to characterize the structure of a novel natural
polysaccharide from Agrocybe aegirita (AAPS) and evaluate its anti-aging activity. The …

A systematic review on the role of melatonin and its mechanisms on diabetes-related reproductive impairment in non-clinical studies

M Armandeh, B Bameri, H Haghi-Aminjan… - Frontiers in …, 2022 - frontiersin.org
Background Diabetes-induced reproductive complications can lead to subfertility and
infertility, raising the need to protect reproductive organs. There are limited medications …