Alzheimer's disease (AD) is the most common form of dementia. AD brain pathology starts
decades before the onset of clinical symptoms. One early pathological hallmark is blood …

The blood–brain barrier (BBB) is a dynamic and complex system which separates the brain
from the blood. It helps to maintain the homeostasis of the brain, which is essential for …

Background Autism spectrum disorders (ASD) are complex conditions whose pathogenesis
may be attributed to gene–environment interactions. There are no definitive mechanisms …

Aging involves a decline in neural function that contributes to cognitive impairment and
disease. However, the mechanisms underlying the transition from a young-and-healthy to …

Objective Acquired epilepsy is frequently associated with structural lesions after trauma,
stroke, and infections. Although seizures are often difficult to treat, there is no clinically …

Epilepsy and Alzheimer's disease (AD) incidence increases with age. There are reciprocal
relationships between epilepsy and AD. Epilepsy is a risk factor for AD and, in turn, AD is an …

Temporal lobe epilepsy (TLE) is the most common form of focal epilepsies in adults. It is
often initiated by an insult or brain injury which triggers a series of alterations which …

Background Disease progression and delayed neurological complications are common after
aneurysmal subarachnoid hemorrhage (aSAH). We explored the potential of quantitative …

The maintenance of blood-brain barrier (BBB) integrity is essential for providing a suitable
environment for nervous tissue function. BBB disruption is involved in many central nervous …

Postinjury epilepsy (PIE) is a devastating sequela of various brain insults. While recent
studies offer novel insights into the mechanisms underlying epileptogenesis and discover …