Osteoblast differentiation is a multistep series of events modulated by an integrated cascade
of gene expression that initially supports proliferation and the sequential expression of …

Publisher Summary This chapter discusses the structure of the cellular and retroviral jun
genes and their relationship to other transcriptional regulators. The interaction between the …

The v-maf oncogene, identified from AS42 avian retrovirus, encodes a nuclear bZip protein.
To elucidate the molecular mechanism of cell transformation induced by this oncogene, we …

The promoter P97 of human papillomavirus-16 (HPV-16) gives rise to transcripts that
encode the principal transforming genes of the virus, E6 and E7. The activity of P97 is …

An overview of the chemical and photochemical probes which over the past ten years have
been used in studies of DNA/ligand complexes and of non‐B‐form DNA conformation is …

The cellular oncogene c–jun is transiently expressed in cultured cells stimulated to
proliferate but has not been identified in normal liver. Because partial hepatectomy results in …

Cell cycle-regulated gene expression is essential for normal cell growth and development
and loss of stringent growth control is associated with the acquisition of the transformed …

Jun is a transcription factor that can also induce oncogenic transformation. Its tional
equivalence. A chimeric GCN4 DNA-binding domain is conserved from yeast to man and …

Polyomavirus (Py) DNA replication is regulated by its enhancer, which contains an AP1 site,
c-Jun and c-Fos, the products of nuclear protooncogenes c-jun and c-fos, form the …

The GRP78 and GRP94 are two constitutively expressed ER resident proteins that are
coordinately induced in response to stress conditions. The control of their induction is at the …