Mitochondria play a key role in both health and disease. Their function is not limited to
energy production but serves multiple mechanisms varying from iron and calcium …

Mitochondria, which serve as the energy factories of cells, are involved in cell differentiation,
calcium homeostasis, amino acid and fatty acid metabolism and apoptosis. In response to …

Stroke is one of the leading causes of death and long-term disability worldwide. More than
80% of strokes are ischemic, caused by an occlusion of cerebral arteries. Without question …

Ferroptosis is a mode of cell death regulated by iron-dependent lipid peroxidation. Growing
evidence suggests ferroptosis induction as a novel anti-cancer modality that could …

Iron is an essential micronutrient for all types of organisms; however, iron has chemical
properties that can be harmful to cells. Because iron is both necessary and potentially …

Mitochondria are essential organelles of mammalian cells, often emphasized for their
function in energy production, iron metabolism and apoptosis as well as heme synthesis …

Highlights•Metal ions affect reproductive physiology in hematophagous and
nonhematophagous insects.•Metal-homeostasis mechanisms may be shared between …

Because of its peculiar redox properties, iron is an essential element in living organisms,
being involved in crucial biochemical processes such as oxygen transport, energy …

Iron, as the most abundant metallic element within the human organism, is an indispensable
ion for sustaining life and assumes a pivotal role in governing glucose and lipid metabolism …

Iron overload associated cardiac dysfunction remains a significant clinical challenge whose
underlying mechanism (s) have yet to be defined. We aim to evaluate the involvement of the …