Abstract Coronavirus disease 2019 (Covid-19) is a worldwide infectious disease caused by
severe acute respiratory coronavirus 2 (SARS-CoV-2). In severe SARS-CoV-2 infection …

Silent information regulator (SIRT) has distinctive enzymatic activities and physiological
functions to control cell-cycle progression, gene expression, and DNA stability by targeting …

Parkinson disease (PD) is a progressive neurodegenerative disease (NDD) of the brain. It
has been reported that prolactin (PRL) hormone plays a differential effect in PD, may be …

It has been illustrated that metabolic syndrome (MetS) is associated with Alzheimer disease
(AD) neuropathology. Components of MetS including central obesity, hypertension, insulin …

Parkinson's disease (PD) is one of the most common degenerative brain disorders caused
by the loss of dopaminergic neurons in the substantia nigra (SN). Lewy bodies and …

SARS-CoV-2 by the direct cytopathic effect or indirectly through the propagation of pro-
inflammatory cytokines could cause endothelial dysfunction (ED) and oxidative stress (OS) …

Parkinson's disease (PD) is a neurodegenerative disorder characterized by the progressive
loss of dopaminergic neurons in the substantia nigra. The hallmarks are the presence of …

Multiple sclerosis (MS) is an autoimmune demyelinating neurodegenerative disease of the
central nervous system (CNS) due to injury of the myelin sheath by immune cells. The …

Parkinson's disease (PD) is a chronic and progressive neurodegenerative disease of the
brain. PD is characterized by motor and non-motor symptoms. The p75 neurotrophin …

Introduction Fenofibrate is an agonist of peroxisome proliferator activated receptor alpha
(PPAR-α), that possesses anti-inflammatory, antioxidant, and anti-thrombotic properties …