Congenital anomalies of the kidney and urinary tract (CAKUT) are the most frequent form of
malformation at birth and represent the cause of 40–50% of pediatric and 7% of adult end …

Carcinomas, cancers of epithelial origin, constitute the majority of all cancers. Loss of
epithelial characteristics is an early step in carcinoma progression. Malignant transformation …

Recurrence of idiopathic focal segmental glomerulosclerosis (FSGS) after renal
transplantation is believed to be caused by a circulating factor (s). We detected cardiotrophin …

The kidney is a key organ in the human body that excretes toxins and sustains the water–
electrolyte balance. During embryonic development and disease progression, the kidney …

Reviews and critical articles covering the entire field of normal anatomy (cytology, histology,
cyto-and histochemistry, electron microscopy, macroscopy, experimental morphology and …

Early kidney development in mammals is characterized by reciprocal tissue interaction
between the ureteric bud and the metanephric mesenchyme. The coordinated response to …

Over 50 years after its discovery in early chick embryos, the concept of epithelial-
mesenchymal transition (EMT) is now widely applied to morphogenetic studies in both …

WT1, a critical regulator of kidney development, is a tumor suppressor for nephroblastoma
but in some contexts functions as an oncogene. A limited number of direct transcriptional …

The ability to form epithelial lumina is a central architectural characteristic of virtually all
organs and indispensable for their function. Ontogenetically, the kidney is one of the best …

The molecular basis of calcineurin inhibitor toxicity (CNIT) in kidney transplantation (KT) and
its contribution to chronic allograft dysfunction (CAD) with interstitial fibrosis (IF) and tubular …