Tooth repair and regeneration: potential of dental stem cells

W Zhang, PC Yelick - Trends in molecular medicine, 2021 - cell.com
Tooth defects are an extremely common health condition that affects millions of individuals.
Currently used dental repair treatments include fillings for caries, endodontic treatment for …

Progress in mesenchymal stem cell therapy for ischemic stroke

Y Guo, Y Peng, H Zeng, G Chen - Stem cells international, 2021 - Wiley Online Library
Ischemic stroke (IS) is a serious cerebrovascular disease with high morbidity and disability
worldwide. Despite the great efforts that have been made, the prognosis of patients with IS …

Periodontal ligament stem cells as a promising therapeutic target for neural damage

F Mohebichamkhorami, R Fattahi, Z Niknam… - Stem Cell Research & …, 2022 - Springer
Background The damaged neuronal cells of adult mammalian lack the regenerative ability to
replace the neuronal connections. Periodontal ligament stem cells (PDLSCs) are the …

Single-Cell Transcriptomic Analysis of Dental Pulp and Periodontal Ligament Stem Cells

Y Yang, T Alves, MZ Miao, YC Wu, G Li… - Journal of Dental …, 2024 - journals.sagepub.com
The regeneration of periodontal, periapical, and pulpal tissues is a complex process
requiring the direct involvement of cells derived from pluripotent stem cells in the periodontal …

Mesenchymal stromal cells derived from dental tissues: immunomodulatory properties and clinical potential

LI Poblano-Pérez, ME Castro-Manrreza… - International Journal of …, 2024 - mdpi.com
Mesenchymal stem/stromal cells (MSCs) are multipotent cells located in different areas of
the human body. The oral cavity is considered a potential source of MSCs because they …

l-Borneol and d-Borneol promote transdifferentiation of astrocytes into neurons in rats by regulating Wnt/Notch pathway to exert neuroprotective effect during recovery …

R Ma, D Lu, Q Xie, J Yuan, M Ren, Y Li, J Wang, J Li… - Phytomedicine, 2023 - Elsevier
Abstract Background The Chinese medicines Borneolum and l-Borneolum have
neuroprotective effects on acute cerebral ischaemia–reperfusion (IR) in rats. Research on …

Dental-Pulp stem cells as a therapeutic strategy for ischemic stroke

C Nito, S Suda, Y Nitahara-Kasahara, T Okada… - Biomedicines, 2022 - mdpi.com
Regenerative medicine aims to restore human functions by regenerating organs and tissues
using stem cells or living tissues for the treatment of organ and tissue defects or dysfunction …

Mesenchymal stem cells and their extracellular vesicles as emerging therapeutic tools in the treatment of ischemic stroke

DIN Pratiwi, S Alhajlah, A Alawadi, A Hjazi, T Alawsi… - Tissue and Cell, 2024 - Elsevier
Ischemic stroke (IS) is a neurological condition characterized by severe long-term
consequences and an unfavorable prognosis for numerous patients. Despite advancements …

Dental pulp stem cell therapy in ischemic stroke: a meta-analysis of preclinical studies

H Wang, M Sun, J Sun, P Gong, N Liu… - Journal of Stroke and …, 2022 - Elsevier
Objective More preclinical research evidence has shown that dental pulp stem cells
(DPSCs) transplantation is expected to promote the recovery of ischemic stroke (IS), but it …

Mesenchymal stromal cells perspective: new potential therapeutic for the treatment of neurological diseases

T Mukai, K Sei, T Nagamura-Inoue - Pharmaceutics, 2021 - mdpi.com
Several studies have shown that mesenchymal stromal/stem cells (MSCs) exert their
neuroprotective and neurorestorative efficacy via the secretion of neurotrophic factors …