[HTML][HTML] Aging, immunity, and COVID-19: how age influences the host immune response to coronavirus infections?

V Bajaj, N Gadi, AP Spihlman, SC Wu, CH Choi… - Frontiers in …, 2021 - frontiersin.org
The novel coronavirus severe acute respiratory syndrome coronavirus 2 causing the
Coronavirus disease (COVID-19) pandemic has ravaged the world with over 72 million total …

[HTML][HTML] Immune response, inflammation, and the clinical spectrum of COVID-19

LF García - Frontiers in immunology, 2020 - frontiersin.org
The current COVID-19 pandemic began in December 2019 in Wuhan (China) and rapidly
extended to become a global sanitary and economic emergency. Its etiological agent is the …

[HTML][HTML] Immune response in COVID-19: A review

MA Chowdhury, N Hossain, MA Kashem… - Journal of infection and …, 2020 - Elsevier
The immune system protects us from viruses and diseases. It produces an antibody to kill
pathogen. This review shows a brief picture about the immune system to protect us from …

COVID‐19 impact on public health, environment, human psychology, global Socioeconomy, and education

Y Miyah, M Benjelloun, S Lairini… - The Scientific World …, 2022 - Wiley Online Library
The end of the year 2019 was marked by the introduction of a third highly pathogenic
coronavirus, after SARS‐CoV (2003) and MERS‐CoV (2012), in the human population …

Epidemiology, pathogenesis, clinical presentations, diagnosis and treatment of COVID-19: a review of current evidence

S Rahman, MTV Montero, K Rowe… - Expert review of …, 2021 - Taylor & Francis
Introduction The COVID-19 pandemic has created a public health crisis, infected millions of
people, and caused a significant number of deaths. SARS-CoV-2 transmits from person to …

[HTML][HTML] A systematic review of pathological findings in COVID-19: a pathophysiological timeline and possible mechanisms of disease progression

SB Polak, IC Van Gool, D Cohen, JH von der Thüsen… - Modern Pathology, 2020 - Elsevier
Since the outbreak of the COVID-19 pandemic, much has been learned regarding its clinical
course, prognostic inflammatory markers, disease complications, and mechanical ventilation …

COVID-19: drug targets and potential treatments

C Gil, T Ginex, I Maestro, V Nozal… - Journal of medicinal …, 2020 - ACS Publications
Currently, humans are immersed in a pandemic caused by the emerging severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), which threatens public health …

COVID-19, mast cells, cytokine storm, psychological stress, and neuroinflammation

D Kempuraj, GP Selvakumar, ME Ahmed… - The …, 2020 - journals.sagepub.com
Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) is a new pandemic infectious disease that originated in China …

[PDF][PDF] Vascular disease and thrombosis in SARS-CoV-2-infected rhesus macaques

M Aid, K Busman-Sahay, SJ Vidal, Z Maliga, S Bondoc… - Cell, 2020 - cell.com
The COVID-19 pandemic has led to extensive morbidity and mortality throughout the world.
Clinical features that drive SARS-CoV-2 pathogenesis in humans include inflammation and …

Complement C3 vs C5 inhibition in severe COVID-19: Early clinical findings reveal differential biological efficacy

DC Mastellos, BGPP da Silva, BAL Fonseca… - Clinical …, 2020 - Elsevier
Growing clinical evidence has implicated complement as a pivotal driver of COVID-19
immunopathology. Deregulated complement activation may fuel cytokine-driven hyper …