M2 macrophage facilitated angiogenesis in cutaneous squamous cell carcinoma via circ_TNFRSF21/miR‐3619‐5p/ROCK axis

J Ma, L Huang, YB Gao, MX Li… - … Kaohsiung Journal of …, 2022 - Wiley Online Library
In recent years, the role of circular RNA in cancer cells has been studied broadly; however,
the functional significance of circular RNA in the regulation of the tumor microenvironment …

Circ-AMOTL1 enhances cardiac fibrosis through binding with EIF4A3 and stabilizing MARCKS expression in diabetic cardiomyopathy

Y Yang, H Yang, C Yang - Cellular Signalling, 2023 - Elsevier
Objective To evaluate the effects and possible mechanisms of circular RNAs (circRNAs) on
diabetic myocardial fibrosis (DMF). Methods We used an in vivo mice model of …

LncRNA SNHG16 regulates RAS and NF-κB pathway-mediated NLRP3 inflammasome activation to aggravate diabetes nephropathy through stabilizing TLR4

Y Liu, M Zhang, H Zhong, N Xie, Y Wang, S Ding… - Acta Diabetologica, 2023 - Springer
Abstract Aims LncRNA SNHG16 and Toll-like receptor-4 (TLR4) participate in diabetes
nephropathy. This study investigated whether SNHG16 regulates diabetic renal injury (DRI) …

Emerging Roles of extracellular vesicle-delivered circular RNAs in atherosclerosis

C Wen, B Li, L Nie, L Mao, Y Xia - Frontiers in Cell and …, 2022 - frontiersin.org
Atherosclerosis (AS) is universally defined as chronic vascular inflammation induced by
dyslipidaemia, obesity, hypertension, diabetes and other risk factors. Extracellular vesicles …

Circ_0000064 knockdown attenuates high glucose-induced proliferation, inflammation and extracellular matrix deposition of mesangial cells through miR-424-5p …

J Li, Y Min, Q Zhao - Clinical and Experimental Nephrology, 2022 - Springer
Abstract Background Circular RNA (circRNA) is widely shown to be associated with the
development of diabetic nephropathy (DN). Our study aimed to further explore the role of …

lncRNA ANRIL accelerates wound healing in diabetic foot ulcers via modulating HIF1A/VEGFA signaling through interacting with FUS

J Wan, Y Bao, LJ Hou, GJ Li, LJ Du… - The Journal of Gene …, 2023 - Wiley Online Library
Background Diabetic foot ulcer (DFU) is a frequently diagnosed complication of diabetes,
and remains a heathcare burden worldwide. However, the pathogenesis of DFU is still …

Diabetes mellitus to accelerated atherosclerosis: Shared cellular and molecular mechanisms in glucose and lipid metabolism

N Zhao, X Yu, X Zhu, Y Song, F Gao, B Yu… - Journal of Cardiovascular …, 2024 - Springer
Diabetes is one of the critical independent risk factors for the progression of cardiovascular
disease, and the underlying mechanism regarding this association remains poorly …

Roles of embryonic lethal abnormal vision-like RNA binding proteins in cancer and beyond

H Cai, D Zheng, Y Yao, L Yang, X Huang… - Frontiers in Cell and …, 2022 - frontiersin.org
Embryonic lethal abnormal vision-like (ELAVL) proteins are RNA binding proteins that were
originally discovered as indispensable regulators of the development and functioning of the …

Circular RNA in autoimmune diseases: special emphasis on regulation mechanism in RA and SLE

Y Huang, Q Xue, C Cheng, Y Wang… - Journal of Pharmacy …, 2023 - academic.oup.com
Background Autoimmune diseases are diseases caused by tissue damage caused by the
body's immune response to autoantibodies. Circular RNAs (CircRNAs) are a kind of special …

Circular RNAs: Potential biomarkers and therapeutic targets for autoimmune diseases

RJ Zhao, WY Zhang, XX Fan - Heliyon, 2024 - cell.com
The outcomes and prognosis of autoimmune diseases depend on early diagnosis and
effective treatments. However, symptoms of early autoimmune diseases are often …