Epilepsy is a common disease of the nervous system characterized by transient brain
dysfunction caused by an abnormal electrical discharge from the brain neurons. The …

Epilepsy, one of the most severe neurological diseases, is characterized by abrupt recurrent
seizures. Despite great progress in the development of antiseizure drugs (ASDs) based on …

Epilepsy is considered a circuit-level dysfunction associated with imbalanced excitation-
inhibition, it is therapeutically necessary to identify key brain regions and related circuits in …

Long-term pharmacotherapy, serving as the main therapeutic approach for epilepsy
prophylaxis, has suffered from limited efficacy and potential side effects because of the …

The neural regulation that is tele-controlled remotely by medical professionals or artificial
intelligence (AI) agents can meet the requirement of rapid, precise, personalized …

Objective Unidentified mechanisms largely restrict the viability of effective therapies in
pharmacoresistant epilepsy. Our previous study revealed that hyperactivity of the subiculum …

Epilepsy is a common brain disorder characterized by recurrent epileptic seizures with
neuronal hyperexcitability. Apart from the classical imbalance between excitatory …

Epileptic networks are characterized as having two states, seizures or more prolonged
interictal periods. However, cellular mechanisms underlying the contribution of interictal …

The advent of optogenetic tools has had a profound impact on modern neuroscience
research, revolutionizing our understanding of the brain. These tools offer a remarkable …

Aims Temporal lobe epilepsy (TLE), often associated with cognitive impairment, is one of the
most common types of medically refractory epilepsy. Deep brain stimulation (DBS) shows …