The glycosylation in SARS-CoV-2 and its receptor ACE2

Y Gong, S Qin, L Dai, Z Tian - Signal Transduction and Targeted …, 2021 - nature.com
Abstract Coronavirus disease 2019 (COVID-19), a highly infectious disease caused by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has infected more than …

NF‐κB signaling in inflammation and cancer

T Zhang, C Ma, Z Zhang, H Zhang, H Hu - MedComm, 2021 - Wiley Online Library
Since nuclear factor of κ‐light chain of enhancer‐activated B cells (NF‐κB) was discovered
in 1986, extraordinary efforts have been made to understand the function and regulating …

[PDF][PDF] A mouse-adapted SARS-CoV-2 induces acute lung injury and mortality in standard laboratory mice

SR Leist, KH Dinnon, A Schäfer, VT Longping, K Okuda… - Cell, 2020 - cell.com
The SARS-CoV-2 pandemic has caused extreme human suffering and economic harm. We
generated and characterized a new mouse-adapted SARS-CoV-2 virus that captures …

HIF-1α promotes SARS-CoV-2 infection and aggravates inflammatory responses to COVID-19

M Tian, W Liu, X Li, P Zhao, MA Shereen… - … and Targeted Therapy, 2021 - nature.com
Cytokine storm induced by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-
2) is a major pathological feature of Coronavirus Disease 2019 (COVID-19) and a crucial …

Role of inflammatory cytokines in COVID-19 patients: A review on molecular mechanisms, immune functions, immunopathology and immunomodulatory drugs to …

AA Rabaan, SH Al-Ahmed, J Muhammad, A Khan… - Vaccines, 2021 - mdpi.com
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), is a severe pandemic of the current century. The vicious …

Lethality of SARS-CoV-2 infection in K18 human angiotensin-converting enzyme 2 transgenic mice

FS Oladunni, JG Park, PA Pino, O Gonzalez… - Nature …, 2020 - nature.com
Vaccine and antiviral development against SARS-CoV-2 infection or COVID-19 disease
would benefit from validated small animal models. Here, we show that transgenic mice …

Selenium deficiency is associated with mortality risk from COVID-19

A Moghaddam, RA Heller, Q Sun, J Seelig… - Nutrients, 2020 - mdpi.com
SARS-CoV-2 infections underlie the current coronavirus disease (COVID-19) pandemic and
are causative for a high death toll particularly among elderly subjects and those with …

The role of cytokines and chemokines in severe acute respiratory syndrome coronavirus 2 infections

RJ Hsu, WC Yu, GR Peng, CH Ye, SY Hu… - Frontiers in …, 2022 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in countless
infections and caused millions of deaths since its emergence in 2019. Coronavirus disease …

Anti-SARS-CoV-2 activities of tanshinone IIA, carnosic acid, rosmarinic acid, salvianolic acid, baicalein, and glycyrrhetinic acid between computational and in vitro …

D Elebeedy, WF Elkhatib, A Kandeil, A Ghanem… - RSC …, 2021 - pubs.rsc.org
Six compounds namely, tanshinone IIA (1), carnosic acid (2), rosmarinic acid (3), salvianolic
acid B (4), baicalein (5), and glycyrrhetinic acid (6) were screened for their anti-SARS-CoV-2 …

Polymeric particle-based therapies for acute inflammatory diseases

ER Brannon, MV Guevara, NJ Pacifici, JK Lee… - Nature Reviews …, 2022 - nature.com
Acute inflammation is essential for initiating and coordinating the body's response to injuries
and infections. However, in acute inflammatory diseases, inflammation is not resolved but …