Diverse applications of nanomedicine

B Pelaz, C Alexiou, RA Alvarez-Puebla, F Alves… - ACS …, 2017 - ACS Publications
The design and use of materials in the nanoscale size range for addressing medical and
health-related issues continues to receive increasing interest. Research in nanomedicine …

[HTML][HTML] Intraoperative imaging-guided cancer surgery: from current fluorescence molecular imaging methods to future multi-modality imaging technology

C Chi, Y Du, J Ye, D Kou, J Qiu, J Wang, J Tian… - Theranostics, 2014 - ncbi.nlm.nih.gov
Cancer is a major threat to human health. Diagnosis and treatment using precision medicine
is expected to be an effective method for preventing the initiation and progression of cancer …

Nanoparticles in practice for molecular-imaging applications: an overview

P Padmanabhan, A Kumar, S Kumar, RK Chaudhary… - Acta biomaterialia, 2016 - Elsevier
Nanoparticles (NPs) are playing a progressively more significant role in multimodal and
multifunctional molecular imaging. The agents like Superparamagnetic iron oxide (SPIO) …

Detection of pancreatic cancer by convolutional-neural-network-assisted spontaneous Raman spectroscopy with critical feature visualization

Z Li, Z Li, Q Chen, A Ramos, J Zhang, JP Boudreaux… - Neural Networks, 2021 - Elsevier
Pancreatic cancer is the deadliest cancer type with a five-year survival rate of less than 9%.
Detection of tumor margins plays an essential role in the success of surgical resection …

Targeted nanotechnology for cancer imaging

R Toy, L Bauer, C Hoimes, KB Ghaghada… - Advanced drug delivery …, 2014 - Elsevier
Targeted nanoparticle imaging agents provide many benefits and new opportunities to
facilitate accurate diagnosis of cancer and significantly impact patient outcome. Due to the …

IGF1 receptor targeted theranostic nanoparticles for targeted and image-guided therapy of pancreatic cancer

H Zhou, W Qian, FM Uckun, L Wang, YA Wang… - ACS …, 2015 - ACS Publications
Overcoming resistance to chemotherapy is a major and unmet medical challenge in the
treatment of pancreatic cancer. Poor drug delivery due to stromal barriers in the tumor …

Emerging fluorescent molecular tracers to guide intra-operative surgical decision-making

P Debie, S Hernot - Frontiers in Pharmacology, 2019 - frontiersin.org
Fluorescence imaging is an emerging technology that can provide real-time information
about the operating field during cancer surgery. Non-specific fluorescent agents, used for …

Fluorescent imaging of cancerous tissues for targeted surgery

L Bu, B Shen, Z Cheng - Advanced drug delivery reviews, 2014 - Elsevier
To maximize tumor excision and minimize collateral damage are the primary goals of cancer
surgery. Emerging molecular imaging techniques have made “image-guided surgery” …

Nanoscale systems for local drug delivery

T Ji, DS Kohane - Nano today, 2019 - Elsevier
Many diseases and conditions affect a relatively localized area of the body. They can be
treated either by direct deposition of drug in the target area, or by giving the drug …

The urokinase receptor (uPAR) as a “Trojan Horse” in targeted cancer therapy: challenges and opportunities

V Metrangolo, M Ploug, LH Engelholm - Cancers, 2021 - mdpi.com
Simple Summary Discovered more than three decades ago, the urokinase-type
plasminogen activator receptor (uPAR) has now firmly established itself as a versatile …