The mammalian proteins MMS19, MIP18, and ANT2 are involved in cytoplasmic iron-sulfur cluster protein assembly
Iron-sulfur (Fe-S) clusters are essential cofactors of proteins with a wide range of biological
functions. A dedicated cytosolic Fe-S cluster assembly (CIA) system is required to assemble …
functions. A dedicated cytosolic Fe-S cluster assembly (CIA) system is required to assemble …
[Fe–S] cluster assembly in the apicoplast and its indispensability in mosquito stages of the malaria parasite
The relict plastid (apicoplast) of the malaria parasite is the site for important biochemical
pathways and is essential for parasite survival. The sulfur mobilization (SUF) pathway of iron …
pathways and is essential for parasite survival. The sulfur mobilization (SUF) pathway of iron …
The conserved protein Dre2 uses essential [2Fe–2S] and [4Fe–4S] clusters for its function in cytosolic iron–sulfur protein assembly
DJA Netz, HM Genau, BD Weiler, E Bill… - Biochemical …, 2016 - portlandpress.com
The cytosolic iron–sulfur (Fe–S) protein assembly (CIA) machinery comprises 11 essential
components and matures Fe–S proteins involved in translation and genome maintenance …
components and matures Fe–S proteins involved in translation and genome maintenance …
An oxygen-dependent interaction between FBXL5 and the CIA-targeting complex regulates iron homeostasis
The iron-sensing protein FBXL5 is the substrate adaptor for a SKP1-CUL1-RBX1 E3
ubiquitin ligase complex that regulates the degradation of iron regulatory proteins (IRPs) …
ubiquitin ligase complex that regulates the degradation of iron regulatory proteins (IRPs) …
¡ Viva la mitochondria!: harnessing yeast mitochondria for chemical production
The mitochondria, often referred to as the powerhouse of the cell, offer a unique
physicochemical environment enriched with a distinct set of enzymes, metabolites and …
physicochemical environment enriched with a distinct set of enzymes, metabolites and …
Iron–sulphur cluster biogenesis via the SUF pathway
Abstract Iron–sulphur (Fe–S) clusters are versatile cofactors, which are essential for key
metabolic processes in cells, such as respiration and photosynthesis, and which may have …
metabolic processes in cells, such as respiration and photosynthesis, and which may have …
[HTML][HTML] Defective mitochondrial ISCs biogenesis switches on IRP1 to fine tune selective mitophagy
Both iron metabolism and mitophagy, a selective mitochondrial degradation process via
autolysosomal pathway, are fundamental for the cellular well-being. Mitochondria are the …
autolysosomal pathway, are fundamental for the cellular well-being. Mitochondria are the …
[HTML][HTML] Excessive by-product formation: a key contributor to low isobutanol yields of engineered Saccharomyces cerevisiae strains
It is theoretically possible to engineer Saccharomyces cerevisiae strains in which isobutanol
is the predominant catabolic product and high-yielding isobutanol-producing strains are …
is the predominant catabolic product and high-yielding isobutanol-producing strains are …
Optical Imaging Opportunities to Inspect the Nature of Cytosolic Iron Pools
RC Hider, C Pourzand, Y Ma, A Cilibrizzi - Molecules, 2023 - mdpi.com
The chemical nature of intracellular labile iron pools (LIPs) is described. By virtue of the
kinetic lability of these pools, it is suggested that the isolation of such species by …
kinetic lability of these pools, it is suggested that the isolation of such species by …
Maturation strategy influences expression levels and cofactor occupancy in Fe–S proteins
M Jansing, S Mielenbrink, H Rosenbach… - JBIC Journal of …, 2023 - Springer
Iron–sulfur clusters are ubiquitous cofactors required for fundamental biological processes.
Structural and spectroscopic analysis of Fe–S proteins is often limited by low cluster …
Structural and spectroscopic analysis of Fe–S proteins is often limited by low cluster …