Arousal may be understood on a spectrum, with excessive sleepiness, cognitive dysfunction,
and inattention on one side, a wakeful state in the middle, and hypervigilance, panic, and …

The locus coeruleus (LC), a small brainstem nucleus, is the primary source of the
neuromodulator norepinephrine (NE) in the brain. The LC receives input from widespread …

During moments involving selective attention, the thalamus orchestrates the preferential
processing of prioritized information by coordinating rhythmic neural activity within a …

The locus coeruleus (LC), the origin of noradrenergic modulation of cognitive and
behavioral function, may play an important role healthy ageing and in neurodegenerative …

Animal and human imaging research reported that the presence of cortical Alzheimer's
Disease's (AD) neuropathology, beta-amyloid and neurofibrillary tau, is associated with …

Many aspects of attention decline with aging. There is a current debate on how aging also
affects sustained attention. In this study, we contribute to this debate by meta-analytically …

Abnormally phosphorylated tau, an indicator of Alzheimer's disease, accumulates in the first
decades of life in the locus coeruleus (LC), the brain's main noradrenaline supply. However …

Hemispheric asymmetries in affective and cognitive functions have been extensively
studied. While both cerebral hemispheres contribute to most affective and cognitive …

Human and non-human animal behavior is highly malleable and adapts successfully to
internal and external demands. Such behavioral success stands in striking contrast to the …

Instantaneous brain states have consequences for our sensation, perception, and
behaviour. Fluctuations in arousal and neural desynchronization likely pose perceptually …