Single‐dose pharmacokinetics and safety of solriamfetol in participants with normal or impaired renal function and with end‐stage renal disease requiring …

K Zomorodi, D Chen, L Lee, K Lasseter… - The Journal of …, 2019 - Wiley Online Library
Abstract Solriamfetol (JZP‐110), a selective dopamine and norepinephrine reuptake
inhibitor with wake‐promoting effects, is renally excreted∼ 90% unchanged within 48 hours …

The bidirectional relationship between obstructive sleep apnea and chronic kidney disease

L Hui, R Benca - Journal of Stroke and Cerebrovascular Diseases, 2021 - Elsevier
Sleep apnea is a condition with significant health risks and increased risk of mortality and is
prevalent in patients with chronic kidney disease. This paper describes the detrimental …

Association of diabetic microvascular complications and parameters of obstructive sleep apnea in patients with type 2 diabetes

R Zhang, P Zhang, F Zhao, X Han… - Diabetes Technology & …, 2016 - liebertpub.com
Background: Obstructive sleep apnea (OSA) is prevalent in patients with type 2 diabetes, but
the influence of OSA on diabetes complications is not clear. We aimed to investigate the …

[HTML][HTML] Anemia and hypoxia impact on chronic kidney disease onset and progression: review and updates

E Habas Sr, A Al Adab, M Arryes, G Alfitori, K Farfar… - Cureus, 2023 - ncbi.nlm.nih.gov
Chronic kidney disease (CKD) is caused by hypoxia in the renal tissue, leading to
inflammation and increased migration of pathogenic cells. Studies showed that leukocytes …

Sudden cardiac death in dialysis: arrhythmic mechanisms and the value of non-invasive electrophysiology

D Poulikakos, K Hnatkova, S Skampardoni… - Frontiers in …, 2019 - frontiersin.org
Sudden Cardiac Death (SCD) is the leading cause of cardiovascular death in dialysis
patients. This review discusses potential underlying arrhythmic mechanisms of SCD in the …

The association of obstructive sleep apnea and renal outcomes—a systematic review and meta-analysis

DW Hwu, KD Lin, KC Lin, YJ Lee, YH Chang - BMC nephrology, 2017 - Springer
Background The aim of this systematic review and meta-analysis was to summarize the
association of obstructive sleep apnea (OSA) with renal outcome. Methods Our study …

Nocturnal hypoxemia severity influences the effect of CPAP therapy on renal renin–angiotensin–aldosterone system activity in humans with obstructive sleep apnea

DDM Nicholl, PJ Hanly, AA Zalucky, GB Handley… - Sleep, 2021 - academic.oup.com
Abstract Study Objectives Nocturnal hypoxemia (NH) in obstructive sleep apnea (OSA) is
associated with renal renin–angiotensin–aldosterone system (RAAS) up-regulation and loss …

Sleep apnea prevalence in chronic kidney disease-association with total body water and symptoms

HC Huang, G Walters, G Talaulikar, D Figurski… - BMC nephrology, 2017 - Springer
Background Sleep apnea is common and associated with poor outcome in severe chronic
kidney disease, but validated screening tools are not available. Our objectives were to …

Sleep disorders: Serious threats among kidney transplant recipients

S Parajuli, R Tiwari, DF Clark, DA Mandelbrot… - Transplantation …, 2019 - Elsevier
In patients with chronic kidney disease (CKD) and kidney transplant recipients who continue
to have some degree of CKD, the prevalence of sleep-related disorders is very high …

[PDF][PDF] Pulmonary hypertension in patients with stage 1-3 chronic kidney disease

QM Yang, XR Bao - Genet Mol Res, 2014 - geneticsmr.com
Pulmonary hypertension (PH) secondary to chronic kidney disease (CKD) is common, but in
stages 1-3 CKD patients, it remains unclear. We sought to evaluate the prevalence of PH …