Spermatogenesis in humans and its affecting factors

FTL Neto, PV Bach, BB Najari, PS Li… - Seminars in cell & …, 2016 - Elsevier
Spermatogenesis is an extraordinary complex process. The differentiation of spermatogonia
into spermatozoa requires the participation of several cell types, hormones, paracrine …

The human epididymis: its function in sperm maturation

R Sullivan, R Mieusset - Human reproduction update, 2016 - academic.oup.com
BACKGROUND Spermatozoa acquire their fertilizing ability and forward motility properties
during epididymal transit. Our knowledge of gamete physiology is based on studies …

The seminal microbiome in health and disease

S Altmäe, JM Franasiak, R Mändar - Nature Reviews Urology, 2019 - nature.com
Owing to the fact that there are more microbial than human cells in our body and that
humans contain more microbial than human genes, the microbiome has huge potential to …

Microfluidics for sperm analysis and selection

R Nosrati, PJ Graham, B Zhang, J Riordon… - Nature Reviews …, 2017 - nature.com
Infertility is a growing global health issue with far-reaching socioeconomic implications. A
downward trend in male fertility highlights the acute need for affordable and accessible …

Exosome composition and seminal plasma proteome: A promising source of biomarkers of male infertility

L Candenas, R Chianese - International journal of molecular sciences, 2020 - mdpi.com
Infertility has become a global health issue, with approximately 50% of infertility cases
generated by disorders in male reproduction. Spermatozoa are conveyed towards female …

Sperm acquire epididymis-derived proteins through epididymosomes

F Barrachina, MA Battistone, J Castillo… - Human …, 2022 - academic.oup.com
STUDY QUESTION Are epididymosomes implicated in protein transfer from the epididymis
to spermatozoa? SUMMARY ANSWER We characterized the contribution of epididymal …

The contribution of human sperm proteins to the development and epigenome of the preimplantation embryo

J Castillo, M Jodar, R Oliva - Human reproduction update, 2018 - academic.oup.com
BACKGROUND Knowledge of the proteomic composition of the gametes is essential to
understand reproductive functions. Most of the sperm proteins are related to …

[HTML][HTML] Semen evaluation: Methodological advancements in sperm quality-specific fertility assessment—A review

BM Tanga, AY Qamar, S Raza, S Bang, X Fang… - Animal …, 2021 - ncbi.nlm.nih.gov
Assessment of male fertility is based on the evaluation of sperm. Semen evaluation
measures various sperm quality parameters as fertility indicators. However, semen …

Role of zinc (Zn) in human reproduction: A journey from initial spermatogenesis to childbirth

S Vickram, K Rohini, S Srinivasan… - International journal of …, 2021 - mdpi.com
Zinc (Zn), the second-most necessary trace element, is abundant in the human body. The
human body lacks the capacity to store Zn; hence, the dietary intake of Zn is essential for …

Semen proteomics and male infertility

M Jodar, A Soler-Ventura, R Oliva… - Journal of …, 2017 - Elsevier
Semen is a complex body fluid containing an admixture of spermatozoa suspended in
secretions from the testes and epididymis which are mixed at the time of ejaculation with …