HIV‐1 replication requires optimal activation of the unfolded protein response

A Tripathi, K Iyer, D Mitra - FEBS letters, 2023 - Wiley Online Library
Several human diseases including viral infections activate the unfolded protein response
(UPR) due to abnormal accumulation of unfolded/misfolded proteins. However, UPR …

The role of endoplasmic reticulum stress in promoting aerobic glycolysis in cancer cells: An overview

AT Jalil, MA Abdulhadi, SA Alkubaisy… - … -Research and Practice, 2023 - Elsevier
Aerobic glycolysis, also known as the Warburg effect, is a metabolic phenomenon frequently
observed in cancer cells, characterized by the preferential utilization of glucose through …

Exploring the Impact of Herbal Therapies on COVID-19 and Influenza: Investigating Novel Delivery Mechanisms for Emerging Interventions

L Fornari Laurindo, L Taynara Marton, G Minniti… - Biologics, 2023 - mdpi.com
Synthetic antivirals and corticosteroids have been used to treat both influenza and the SARS-
CoV-2 disease named COVID-19. However, these medications are not always effective …

Natural Product Cordycepin (CD) Inhibition for NRP1/CD304 Expression and Possibly SARS-CoV-2 Susceptibility Prevention on Cancers

T Li, N Luo, J Fu, J Du, Z Liu, Q Tan, M Zheng, J He… - Microorganisms, 2023 - mdpi.com
NRP1/CD304 is a typical membrane-bound co-receptor for the vascular endothelial cell
growth factor (VEGF), semaphorin family members, and viral SARS-CoV-2. Cordycepin (CD) …

Prediction of the binding location between the nuclear inhibitor of DNA binding and differentiation 2 (ID2) and HSPA5

AA Elfiky - Pathology-Research and Practice, 2024 - Elsevier
Abstract Glucose-regulated protein 78 (GRP78), also termed HSPA5, was widely studied in
cancer. It was recently approved that GRP78 has nuclear localization potential that sheds …

The analysis of inducible family members in the water flea Daphnia magna led to the identification of an uncharacterized lineage of heat shock protein 70

X Wu, Z Zhang, W Cui, L Han, Z Liu, X Song, J Tan - Heliyon, 2024 - cell.com
To explore the function and evolutionary relationships of inducible heat shock protein 70
(Hsp70) in Daphnia magna, cDNAs of four Hsp70 family members (DmaHsp70, DmaHsp70 …

Multidimensional pan-cancer analysis of HSPA5 and its validation in the prognostic value of bladder cancer

YX Wang, J Wang, Y Liu, XL Wang, MH Ren - Heliyon, 2024 - cell.com
Endoplasmic reticulum (ER) stress-related genes are closely related to the occurrence,
development, and immunotherapy response of tumors. This study provides a …

[PDF][PDF] Mitochondria in COVID-19: from cellular and molecular perspective

M Rurek - Frontiers in Physiology, 2024 - researchgate.net
SARS-CoV-2 (severe acute respiratory syndrome-coronavirus-2), an RNA-containing virus
belonging to the Coronaviridae family, is a causative agent of COVID-19 (from CoronaVirus …

[HTML][HTML] GRP78-c-Src 信号通路介导周期性牵张力作用下牙周膜成纤维细胞成骨分化的机制研究

胡静, 崔智华, 黄克强, 苏荣健, 赵颂 - West China Journal of …, 2024 - ncbi.nlm.nih.gov
GRP78-c-Src信号通路介导周期性牵张力作用下牙周膜成纤维细胞成骨分化的机制研究- PMC
Back to Top Skip to main content NIH NLM Logo Access keys NCBI Homepage MyNCBI …

BiP/GRP78 is a pro-viral factor for diverse dsDNA viruses that promotes the survival and proliferation of cells upon KSHV infection

G Najarro, K Brackett, H Woosley, C Faeldonea… - bioRxiv, 2023 - biorxiv.org
The Endoplasmic Reticulum (ER)-resident HSP70 chaperone BiP (HSPA5) plays a crucial
role in maintaining and restoring protein folding homeostasis in the ER. BiP function is often …