Depression is the most common mental disorder and a leading cause of disability
worldwide. Despite abundant research, the precise mechanisms underlying the …

The discovery of robust antidepressant actions exerted by the N-methyl-D-aspartate receptor
(NMDAR) antagonist (R, S)-ketamine has been a crucial breakthrough in mood disorder …

Abstract The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has resulted in a serious public …

The human body harbors a diverse ecosystem of microorganisms, including bacteria,
viruses, and fungi, collectively known as the microbiota. Current research is increasingly …

The gut microbiome exerts a considerable influence on human neurophysiology and mental
health. Interactions between intestinal microbiology and host regulatory systems have now …

The emergence of the coronavirus disease 2019 pandemic has dramatically increased the
global prevalence of depression. Unfortunately, antidepressant drugs benefit only a small …

The spleen, an important tissue for the immune system, acts as a filter for blood within the
immune system. Accumulating evidence suggests that the spleen affects a number of brain …

The α7 subtype of the nicotinic acetylcholine receptor (α7 nAChR: coded by Chrna7)
regulates the cholinergic ascending anti-inflammatory pathway involved in depression. We …

Antibiotics are recognised as, on occasion, producing psychiatric side effects, most notably
depression and anxiety. Apart from antimicrobial activity, antibiotics have multiple off‐target …

Depression is a worldwide disease causing severe disability, morbidity, and mortality.
Despite abundant studies, the precise mechanisms underlying the pathophysiology of …