Early life stress and development: potential mechanisms for adverse outcomes

KE Smith, SD Pollak - Journal of neurodevelopmental disorders, 2020 - Springer
Background Chronic and/or extreme stress in early life, often referred to as early adversity,
childhood trauma, or early life stress, has been associated with a wide range of adverse …

Non-genetic factors in schizophrenia

SA Stilo, RM Murray - Current psychiatry reports, 2019 - Springer
Abstract Purpose of Review We review recent developments on risk factors in
schizophrenia. Recent Findings The way we think about schizophrenia today is profoundly …

Rethinking concepts and categories for understanding the neurodevelopmental effects of childhood adversity

KE Smith, SD Pollak - Perspectives on psychological science, 2021 - journals.sagepub.com
Discovering the processes through which early adverse experiences affect children's
nervous-system development, health, and behavior is critically important for developing …

[HTML][HTML] COVID-19 vaccination for people with severe mental illness: why, what, and how?

V Mazereel, K Van Assche, J Detraux… - The Lancet …, 2021 - thelancet.com
Psychiatric disorders, and especially severe mental illness, are associated with an
increased risk of severe acute respiratory syndrome coronavirus 2 infection and COVID-19 …

Developmental trajectories of early life stress and trauma: a narrative review on neurobiological aspects beyond stress system dysregulation

A Agorastos, P Pervanidou, GP Chrousos… - Frontiers in …, 2019 - frontiersin.org
Early life stressors display a high universal prevalence and constitute a major public health
problem. Prolonged psychoneurobiological alterations as sequelae of early life stress (ELS) …

The adverse childhood experiences questionnaire: Two decades of research on childhood trauma as a primary cause of adult mental illness, addiction, and medical …

EM Zarse, MR Neff, R Yoder, L Hulvershorn… - Cogent …, 2019 - Taylor & Francis
Abstract Objective. In 1998, Felitti and colleagues published the first study of the Adverse
Childhood Experiences-Questionnaire (ACE-Q), a 10-item scale used to correlate childhood …

Is the HPA axis as target for depression outdated, or is there a new hope?

A Menke - Frontiers in psychiatry, 2019 - frontiersin.org
Major depressive disorder (MDD) is a very common stress-related mental disorder that
carries a huge burden for affected patients and the society. It is associated with a high …

Depression heterogeneity and its biological underpinnings: toward immunometabolic depression

Y Milaneschi, F Lamers, M Berk, BWJH Penninx - Biological psychiatry, 2020 - Elsevier
Epidemiological evidence indicates the presence of dysregulated homeostatic biological
pathways in depressed patients, such as increased inflammation and disrupted energy …

Neurobiology of resilience: interface between mind and body

F Cathomas, JW Murrough, EJ Nestler, MH Han… - Biological …, 2019 - Elsevier
Stress-related neuropsychiatric disorders, such as major depressive disorder and
posttraumatic stress disorder, exact enormous socioeconomic and individual consequences …

Intergenerational trauma in Latinxs: A scoping review

JP Cerdeña, LM Rivera, JM Spak - Social Science & Medicine, 2021 - Elsevier
Rationale Intergenerational trauma refers to emotional and psychological wounding that is
transmitted across generations. Latinxs—individuals who have migrated from Latin America …