Oncomodulins (OCMs), also known as non-α-parvalbumins, are small molecules known for
their high-affinity binding of Ca 2+ ions. They play crucial roles as Ca 2+ buffers and …

Mutations in PKD1 and PKD2 cause autosomal dominant polycystic kidney disease
(ADPKD), which is characterized by the formation of fluid‐filled cysts in the kidney. In a …

Quantitative proteomics was used to reveal biochemical differences in kidneys of marine
and freshwater three-spined sticklebacks. More than 1500 unambiguous proteins were …

Purpose Hepatocellular carcinoma is the most common primary liver cancer, with poor
prognosis. Complex immune microenvironment of the liver is linked to the development of …

Parvalbumin (PA) is a classical EF-hand calcium-binding protein of muscle, neuronal, and
other tissues, and a major fish allergen. Although certain apo-PAs lack tertiary structure …

The kidney is a highly complex organ equipped with a multitude of miniscule filter-tubule
units called nephrons. Each nephron can be subdivided into multiple segments, each with …

Hypertension can originate from pre-and post-natal insults. High-fat (HF) diet and prenatal
dexamethasone (DEX) exposure are both involved in hypertension of developmental …

Ca2+ is an important second messenger that translates extracellular stimuli into intracellular
responses. Although there has been significant progress in understanding Ca2+ dynamics …

To investigate the single nucleotide polymorphism (SNP) loci of the small albumin (PVALB)
gene in Tibetan and York pigs and the expression pattern in the leg and longest dorsal …

Abstract Calcium‐sensing receptor (CaSR), a family CG‐protein‐coupled receptor, plays a
crucial role in regulating calcium homeostasis by sensing small concentration changes of …