Chronic hepatitis B (CHB) infection functional cure is defined as sustained loss of HBsAg
and several therapeutic strategies are in clinical development designed to …

Exhausted T cells in the tumor microenvironment are major targets of immunotherapies.
However, the exhaustion status of CD8+ tumor-infiltrating lymphocytes (TILs) in bladder …

Introduction Hepatocellular carcinoma (HCC) is the most common primary liver cancer and
fourth-leading cause of cancer death. While drug discovery to improve disease survival was …

Hepatocellular carcinoma (HCC) is considered an immunogenic tumor that arises in
chronically inflamed livers due to underlying chronic liver disease caused by viral and non …

Immune checkpoint inhibitors (ICIs) have shown unprecedented benefits in various adult
cancers, and this success has prompted the exploration of ICI therapy even in childhood …

Despite major advances in immunotherapy, hepatocellular carcinoma (HCC) remains a
challenging target. Natural Killer (NK) cells are crucial components of the anti-HCC immune …

Hepatocellular carcinoma (HCC) is one of the most prevalent and fatal digestive tumors.
Treatment for this disease has been constraint by heterogeneity of this group of tumors …

The increasing set of liver-directed therapies (LDT) have become an integral part of
hepatocellular carcinoma (HCC) treatment. These range from percutaneous ablative …

Transcriptome Profiling Identifies TIGIT as a Marker of T‐Ce... : Hepatology Transcriptome
Profiling Identifies TIGIT as a Marker of T‐Cell Exhaustion in Liver Cancer : Hepatology AASLD …

Natural killer (NK) cells account for 25–50% of the total number of hepatic lymphocytes,
which implicates that NK cells play an important role in liver immunity. The frequencies of …