L Du, Y Yang, X Zhang - Cellular & molecular immunology, 2021 - nature.com
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) initiates the infection process by binding to the viral cellular receptor angiotensin-converting enzyme 2 through …
A Deshpande, BD Harris, L Martinez-Sobrido… - Frontiers in …, 2021 - frontiersin.org
Severe acute respiratory syndrome coronavirus-2 (SAR-CoV-2) causes coronavirus disease 2019 (COVID19) that is responsible for short and long-term disease, as well as death, in …
E Urano, Y Itoh, T Suzuki, T Sasaki… - Science translational …, 2023 - science.org
The Omicron variant continuously evolves under the humoral immune pressure exerted by vaccination and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection …
Humoral immunity to SARS-CoV-2 can be supplemented with polyclonal sera from convalescent donors or an engineered monoclonal antibody (mAb) product. While …
HA Parray, S Shukla, R Perween, R Khatri… - Applied Microbiology …, 2021 - Springer
The route of administration of a therapeutic agent has a substantial impact on its success. Therapeutic antibodies are usually administered systemically, either directly by intravenous …
J Liu, F Mao, J Chen, S Lu, Y Qi, Y Sun, L Fang… - Nature …, 2023 - nature.com
Many of the currently available COVID-19 vaccines and therapeutics are not effective against newly emerged SARS-CoV-2 variants. Here, we developed the metallo-enzyme …
T Arimori, N Ikemura, T Okamoto, J Takagi… - Trends in …, 2022 - cell.com
Decoy receptor proteins that trick viruses to bind to them should be resistant to viral escape because viruses that require entry receptors cannot help but bind decoy receptors …
WR Strohl, Z Ku, Z An, SF Carroll, BA Keyt, LM Strohl - BioDrugs, 2022 - Springer
The COVID-19 pandemic is now approaching 2 years old, with more than 440 million people infected and nearly six million dead worldwide, making it the most significant pandemic …
H Ma, X Zhang, W Zeng, J Zhou, X Chi, S Chen… - Cell Discovery, 2022 - nature.com
Abstract Current SARS-CoV-2 Omicron subvariants impose a heavy burden on global health systems by evading immunity from most developed neutralizing antibodies and vaccines …