The prevalence of obesity and associated chronic diseases continues to increase
worldwide, negatively impacting on societies and economies. Whereas the association …

Obesity is a prevalent global public health issue characterized by excess body fat. Adipose
tissue is now recognized as an important endocrine organ releasing an abundance of …

For any given level of overall adiposity, individuals vary considerably in fat distribution. The
inherited basis of fat distribution in the general population is not fully understood. Here, we …

Sex differences in complex traits are suspected to be in part due to widespread gene-by-sex
interactions (GxSex), but empirical evidence has been elusive. Here, we infer the mixture of …

Introduction: Most medical diagnoses present somewhat differently in men and women,
more so at specific periods of life. Treatment effects may also differ. This is true for …

Objective Aging causes changes in body composition, in which differences in the distribution
and amount of fat and muscle tissue affect the development of various diseases according to …

Sex differences in adipose tissue distribution and function are associated with sex
differences in cardiometabolic disease. While many studies have revealed sex differences in …

Metabolic syndrome (MetS) is a complex disorder characterized by a cluster of metabolic
abnormalities, including abdominal obesity, hypertension, elevated triglycerides, reduced …

The gonadal steroids, including androgens, estrogens and progestogens, are involved in
the control of body fat distribution in humans. Nevertheless, not only the size and localization …

Background: Cardiac troponin concentrations are lower in women than men. We examined
whether age-and risk factor-related changes in cardiac troponin over the life course differ by …