[HTML][HTML] Broadly neutralizing antibodies against COVID-19
The COVID-19 pandemic caused by SARS-CoV-2 has led to hundreds of millions of
infections and millions of deaths, however, human monoclonal antibodies (mAbs) can be an …
infections and millions of deaths, however, human monoclonal antibodies (mAbs) can be an …
Distinct conformations of SARS-CoV-2 Omicron spike protein and its interaction with ACE2 and antibody
Since November 2021, Omicron has been the dominant severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) variant that causes the coronavirus disease 2019 (COVID-19) …
coronavirus 2 (SARS-CoV-2) variant that causes the coronavirus disease 2019 (COVID-19) …
Bispecific antibodies combine breadth, potency, and avidity of parental antibodies to neutralize sarbecoviruses
SARS-CoV-2 variants evade current monoclonal antibody therapies. Bispecific antibodies
(bsAbs) combine the specificities of two distinct antibodies taking advantage of the avidity …
(bsAbs) combine the specificities of two distinct antibodies taking advantage of the avidity …
Rational in silico design identifies two mutations that restore UT28K SARS-CoV-2 monoclonal antibody activity against Omicron BA. 1
T Ozawa, Y Ikeda, L Chen, R Suzuki, A Hoshino… - Structure, 2024 - cell.com
SARS-CoV-2 rapidly mutates and acquires resistance to neutralizing antibodies. We report
an in-silico-designed antibody that restores the neutralizing activity of a neutralizing …
an in-silico-designed antibody that restores the neutralizing activity of a neutralizing …
[HTML][HTML] Bispecific antibodies with broad neutralization potency against SARS-CoV-2 variants of concern
The ongoing emergence of SARS-CoV-2 variants of concern (VOCs) that reduce the
effectiveness of antibody therapeutics necessitates development of next-generation …
effectiveness of antibody therapeutics necessitates development of next-generation …
[HTML][HTML] Function and mechanism of bispecific antibodies targeting SARS-CoV-2
As the dynamic evolution of SARS-CoV-2 led to reduced efficacy in monoclonal neutralizing
antibodies and emergence of immune escape, the role of bispecific antibodies becomes …
antibodies and emergence of immune escape, the role of bispecific antibodies becomes …
[PDF][PDF] Cell Insight
T Liu, J Liu, H Chen, X Zhou, W Fu, Y Cao, J Yang - Cell, 2022 - realmofcaring.org
Type 2 immunity in the lung protects against pathogenic infection and facilitates tissue
repair, but its dysregulation may lead to severe human diseases. Notably, cannabis usage …
repair, but its dysregulation may lead to severe human diseases. Notably, cannabis usage …