Distinctive patterns of microRNA expression in primary muscular disorders
The primary muscle disorders are a diverse group of diseases caused by various defective
structural proteins, abnormal signaling molecules, enzymes and proteins involved in …
structural proteins, abnormal signaling molecules, enzymes and proteins involved in …
Reciprocal regulation of microRNA-1 and insulin-like growth factor-1 signal transduction cascade in cardiac and skeletal muscle in physiological and pathological …
L Elia, R Contu, M Quintavalle, F Varrone, C Chimenti… - Circulation, 2009 - Am Heart Assoc
Background—MicroRNAs (miRNAs/miRs) are small conserved RNA molecules of 22
nucleotides that negatively modulate gene expression primarily through base paring to the …
nucleotides that negatively modulate gene expression primarily through base paring to the …
miR-24 inhibits apoptosis and represses Bim in mouse cardiomyocytes
L Qian, LW Van Laake, Y Huang, S Liu… - Journal of Experimental …, 2011 - rupress.org
Acute myocardial infarction (MI) involves necrotic and apoptotic loss of cardiomyocytes. One
strategy to salvage ischemic cardiomyocytes is to modulate gene expression to promote cell …
strategy to salvage ischemic cardiomyocytes is to modulate gene expression to promote cell …
Most Caenorhabditis elegans microRNAs are individually not essential for development or viability
MicroRNAs (miRNAs), a large class of short noncoding RNAs found in many plants and
animals, often act to post-transcriptionally inhibit gene expression. We report the generation …
animals, often act to post-transcriptionally inhibit gene expression. We report the generation …
The muscle-specific microRNAs miR-1 and miR-133 produce opposing effects on apoptosis by targeting HSP60, HSP70 and caspase-9 in cardiomyocytes
C Xu, Y Lu, Z Pan, W Chu, X Luo, H Lin… - Journal of cell …, 2007 - journals.biologists.com
The microRNAs miR-1 and miR-133 are preferentially expressed in cardiac and skeletal
muscles and have been shown to regulate differentiation and proliferation of these cells. We …
muscles and have been shown to regulate differentiation and proliferation of these cells. We …
MicroRNA-206: the skeletal muscle-specific myomiR
JJ McCarthy - Biochimica et Biophysica Acta (BBA)-Gene Regulatory …, 2008 - Elsevier
MicroRNAs (miRNAs) are a class of non-coding RNAs involved in post-transcriptional gene
silencing. A small number of striated muscle-specific miRNAs have been identified and …
silencing. A small number of striated muscle-specific miRNAs have been identified and …
MicroRNA-1 and-499 regulate differentiation and proliferation in human-derived cardiomyocyte progenitor cells
JPG Sluijter, A van Mil, P van Vliet… - … , and vascular biology, 2010 - Am Heart Assoc
Objective—To improve regeneration of the injured myocardium, it is necessary to enhance
the intrinsic capacity of the heart to regenerate itself and/or replace the damaged tissue by …
the intrinsic capacity of the heart to regenerate itself and/or replace the damaged tissue by …
microRNAs in vertebrate physiology and human disease
TC Chang, JT Mendell - Annu. Rev. Genomics Hum. Genet., 2007 - annualreviews.org
Over the past five years, the importance of a diverse class of 18–24 nucleotide RNA
molecules, known as microRNAs (miRNAs) has increasingly been recognized. These highly …
molecules, known as microRNAs (miRNAs) has increasingly been recognized. These highly …
MicroRNAs 1, 133, and 206: critical factors of skeletal and cardiac muscle development, function, and disease
microRNAs (miRNAs) are a class of highly conserved small non-coding RNAs that
negatively regulate gene expression post-transcriptionally. miRNAs are known to mediate …
negatively regulate gene expression post-transcriptionally. miRNAs are known to mediate …
MicroRNA functions in insects
S Asgari - Insect biochemistry and molecular biology, 2013 - Elsevier
MicroRNAs (miRNAs) are small non-coding RNAs that are generated in all eukaryotes and
viruses. Their role as master regulators of gene expression in various biological processes …
viruses. Their role as master regulators of gene expression in various biological processes …