[HTML][HTML] The human connectome project: a retrospective

JS Elam, MF Glasser, MP Harms, SN Sotiropoulos… - NeuroImage, 2021 - Elsevier
Abstract The Human Connectome Project (HCP) was launched in 2010 as an ambitious
effort to accelerate advances in human neuroimaging, particularly for measures of brain …

Genetic architecture of schizophrenia: a review of major advancements

SE Legge, ML Santoro, S Periyasamy… - Psychological …, 2021 - cambridge.org
Schizophrenia is a severe psychiatric disorder with high heritability. Consortia efforts and
technological advancements have led to a substantial increase in knowledge of the genetic …

Integrative omics of schizophrenia: from genetic determinants to clinical classification and risk prediction

F Guan, T Ni, W Zhu, LK Williams, LB Cui, M Li… - Molecular …, 2022 - nature.com
Schizophrenia (SCZ) is a debilitating neuropsychiatric disorder with high heritability and
complex inheritance. In the past decade, successful identification of numerous susceptibility …

Single-cell dissection of schizophrenia reveals neurodevelopmental-synaptic link and transcriptional resilience associated cellular state

B Ruzicka, S Mohammadi… - Biological …, 2021 - biologicalpsychiatryjournal.com
Background Schizophrenia is a severe mental illness afflicting young adults just as they
approach their full potential, often resulting in a lifetime of severe disability. While many …

The genetic architecture of schizophrenia: review of large-scale genetic studies

H Kato, H Kimura, I Kushima, N Takahashi… - Journal of Human …, 2023 - nature.com
Schizophrenia is a complex and often chronic psychiatric disorder with high heritability.
Diagnosis of schizophrenia is still made clinically based on psychiatric symptoms; no …

[HTML][HTML] Derivation and utility of schizophrenia polygenic risk associated multimodal MRI frontotemporal network

S Qi, J Sui, G Pearlson, J Bustillo… - Nature …, 2022 - nature.com
Schizophrenia is a highly heritable psychiatric disorder characterized by widespread
functional and structural brain abnormalities. However, previous association studies …

Childhood trauma is linked to decreased temporal stability of functional brain networks in young adults

D Huang, Z Liu, H Cao, J Yang, Z Wu, Y Long - Journal of affective …, 2021 - Elsevier
Background Both childhood trauma and disruptions in brain functional networks are
implicated in the development of psychiatric disorders in early adulthood. However, the …

Disrupted intrinsic functional brain network in patients with late-life depression: Evidence from a multi-site dataset

W Tan, X Ouyang, D Huang, Z Wu, Z Liu, Z He… - Journal of Affective …, 2023 - Elsevier
Background Late-life depression (LLD) is a common and serious mental disorder, whose
neural mechanisms are not yet fully understood. In this study, we aimed to characterize LLD …

A functional connectome-based neural signature for individualized prediction of antipsychotic response in first-episode psychosis

H Cao, T Lencz, JA Gallego, JM Rubio… - American Journal of …, 2023 - Am Psychiatric Assoc
Objective: Identification of robust biomarkers that predict individualized response to
antipsychotic treatment at the early stage of psychotic disorders remains a challenge in …

Schizophrenia and psychedelic state: Dysconnection versus hyper-connection. A perspective on two different models of psychosis stemming from dysfunctional …

J Sapienza, M Bosia, M Spangaro, F Martini… - Molecular …, 2023 - nature.com
Psychotic symptoms are a cross-sectional dimension affecting multiple diagnostic
categories, despite schizophrenia represents the prototype of psychoses. Initially, dopamine …