[HTML][HTML] Role of NLRP3 inflammasome in diabetes and COVID-19 role of NLRP3 inflammasome in the pathogenesis and treatment of COVID-19 and diabetes NLRP3 …

J Zhang, X Ma, F Liu, D Zhang, J Ling, Z Zhu… - Frontiers in …, 2023 - frontiersin.org
2019 Coronavirus Disease (COVID-19) is a global pandemic caused by severe acute
respiratory syndrome coronavirus-2 (SARS-CoV-2). A “cytokine storm”, ie, elevated levels of …

Signaling pathways in macrophages: molecular mechanisms and therapeutic targets

M Li, M Wang, Y Wen, H Zhang, GN Zhao, Q Gao - MedComm, 2023 - Wiley Online Library
Macrophages play diverse roles in development, homeostasis, and immunity. Accordingly,
the dysfunction of macrophages is involved in the occurrence and progression of various …

[HTML][HTML] Colchicine and aspirin in community patients with COVID-19 (ACT): an open-label, factorial, randomised, controlled trial

JW Eikelboom, SS Jolly, EP Belley-Cote… - The Lancet …, 2022 - thelancet.com
Background The large number of patients worldwide infected with the SARS-CoV-2 virus
has overwhelmed health-care systems globally. The Anti-Coronavirus Therapies (ACT) …

[PDF][PDF] From emergence to endemicity: a comprehensive review of COVID-19

R Naik, S Avula, SK Palleti, J Gummadi… - Cureus, 2023 - cureus.com
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), later renamed coronavirus
disease 2019 (COVID-19), was first identified in Wuhan, China, in early December 2019 …

Risk factors for postdischarge major thromboembolism and mortality in hospitalized patients with COVID-19 with cardiovascular comorbidities: Insights from the CORE …

D Giannis, M Goldin, H Rahman… - Thrombosis and …, 2023 - thieme-connect.com
Background Coronavirus disease 2019 (COVID-19) is associated with venous and arterial
thromboembolism (VTE and ATE) and all-cause mortality (ACM) in hospitalized patients …

Aspirin and P2Y12 inhibitors in treating COVID-19

A Khalaji, AH Behnoush, S Peiman - European Journal of Internal …, 2023 - ejinme.com
Aspirin and P2Y12 inhibitors in treating COVID-19 - European Journal of Internal Medicine
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[HTML][HTML] 2023 ISTH update of the 2022 ISTH guidelines for antithrombotic treatment in COVID-19

S Schulman, DM Arnold, CA Bradbury… - Journal of thrombosis …, 2024 - Elsevier
Based on emerging evidence from the COVID-19 pandemic, the International Society on
Thrombosis and Haemostasis (ISTH) guidelines for antithrombotic treatment in COVID-19 …

[HTML][HTML] Potential application of sucrose acetate isobutyrate, and glyceryl monooleate for nanonization and bioavailability enhancement of rivaroxaban tablets

AA Al-Shoubki, MH Teaima, R Abdelmonem… - Pharmaceutical Science …, 2024 - Elsevier
This study aimed to investigate the use of Sucrose acetate isobutyrate (SAIB) and Glyceryl
monooleate (GMO) as co-formers for creating Cubosomes and SAIB-based nanodispersions …

Colchicine for the treatment of patients with COVID-19: an updated systematic review and meta-analysis of randomised controlled trials

HA Cheema, U Jafar, A Shahid, W Masood… - BMJ open, 2024 - bmjopen.bmj.com
Objectives We conducted an updated systematic review and meta-analysis to investigate the
effect of colchicine treatment on clinical outcomes in patients with COVID-19. Design …

Investigational pharmacological agents for the treatment of ARDS

K Aribindi, M Lim, S Lakshminrusimha… - Expert Opinion on …, 2024 - Taylor & Francis
ABSTRACT Introduction Acute Respiratory Distress Syndrome (ARDS) is a heterogeneous
form of lung injury with severe hypoxemia and bilateral infiltrates after an inciting event that …