Androgens during infancy, childhood, and adolescence: physiology and use in clinical practice

KA Mason, MJ Schoelwer, AD Rogol - Endocrine Reviews, 2020 - academic.oup.com
We provide an in-depth review of the role of androgens in male maturation and
development, from the fetal stage through adolescence into emerging adulthood, and …

Clinical biochemistry of dihydrotestosterone

PM Marchetti, JH Barth - Annals of Clinical Biochemistry, 2013 - journals.sagepub.com
Dihydrotestosterone (DHT) is the most potent natural androgen in humans. There has been
an increasing interest in this androgen and its role in the development of primary and …

Lowered serum testosterone concentration is associated with enhanced inflammation and worsened lipid profile in men

M Grandys, J Majerczak, J Zapart-Bukowska… - Frontiers in …, 2021 - frontiersin.org
The negative relationship between testosterone and inflammatory cytokines has been
reported for decades, although the exact mechanisms of their interactions are still not clear …

Female sex protects from organ failure and sepsis after major trauma haemorrhage

H Trentzsch, U Nienaber, M Behnke, R Lefering, S Piltz - Injury, 2014 - Elsevier
Introduction Biological sex is considered a risk factor for adverse outcome after major
trauma. We hypothesized that female sex is protective against organ failure, sepsis and …

Maintenance of muscle mass in adult male mice is independent of testosterone

A Davidyan, S Pathak, K Baar, SC Bodine - PloS one, 2021 - journals.plos.org
Testosterone is considered a potent anabolic agent in skeletal muscle with a well-
established role in adolescent growth and development in males. However, the role of …

Associations between prediagnostic concentrations of circulating sex steroid hormones and esophageal/gastric cardia adenocarcinoma among men

JL Petrick, PL Hyland, P Caron, RT Falk… - JNCI: Journal of the …, 2019 - academic.oup.com
Background Esophageal adenocarcinoma (EA) and gastric cardia adenocarcinoma (GCA)
are characterized by a strong male predominance. Concentrations of sex steroid hormones …

Sex differences in neuromuscular aging: The role of sex hormones

J Piasecki, J Škarabot, P Spillane… - Exercise and Sport …, 2024 - journals.lww.com
Males and females experience different trajectories of neuromuscular function across the
lifespan, with females demonstrating accelerated deconditioning in later life. We …

Association between circulating levels of sex steroid hormones and esophageal adenocarcinoma in the FINBAR Study

JL Petrick, RT Falk, PL Hyland, P Caron, RM Pfeiffer… - PloS one, 2018 - journals.plos.org
Background Esophageal adenocarcinoma (EA) is characterized by a strong male
predominance. Sex steroid hormones have been hypothesized to underlie this sex disparity …

The influence of sex, age and heritability on human skeletal muscle carnosine content

A Baguet, I Everaert, E Achten, M Thomis, W Derave - Amino acids, 2012 - Springer
The dipeptide carnosine is found in high concentrations in human skeletal muscle and
shows large inter-individual differences. Sex and age are determining factors, however …

Differential associations of testosterone, dihydrotestosterone and oestradiol with physical, metabolic and health‐related factors in community‐dwelling men aged 17 …

BB Yeap, MW Knuiman, ML Divitini… - Clinical …, 2014 - Wiley Online Library
Objectives Lower testosterone (T) levels are associated with poorer health outcomes in
older men, but associations in younger or middle‐aged men are uncertain, and data for …