[HTML][HTML] Вопросы терапии умеренных когнитивных нарушений

ЛА Щепанкевич, ИА Грибачева… - Неврология …, 2022 - cyberleninka.ru
Развитию деменции предшествуют умеренные когнитивные нарушения (УКН),
лечение которых может замедлить трансформацию УКН в деменцию. В статье …

Sirtuins in Aging

BJ Morris - Encyclopedia of Gerontology and Population Aging, 2022 - Springer
Purpose Early identification of neurocognitive disorder (cognitive impairment) in older adults
is critical and necessary. Early identification allows for additional time for prevention efforts …

[HTML][HTML] Preischemic treadmill exercise ameliorates memory impairment and microvasculature damage in rat model of chronic cerebral hypoperfusion

JM Lee, J Park, JH Lee, MK Song… - International …, 2021 - ncbi.nlm.nih.gov
Purpose Silent information regulator 1 (SIRT1) in the brain is essential for maintaining
cellular homeostasis and plays a neuroprotective role in cerebral ischemia and …

RETRACTED ARTICLE: Laquinimod inhibits MMP+ induced NLRP3 inflammasome activation in human neuronal cells

X Zhang, J Jin, A Xie - Immunopharmacology and …, 2020 - Taylor & Francis
We, the Editor and Publisher of the journal Immunopharmacology and Immunotoxicology,
have retracted the following article: Laquinimod inhibits MMP+-induced NLRP3 …

Desoxyrhapontigenin attenuates neuronal apoptosis in an isoflurane-induced neuronal injury model by modulating the TLR-4/cyclin B1/Sirt-1 pathway

F Liang, X Fu, Y Li, F Han - AMB Express, 2020 - Springer
This study investigated the protective effect of desoxyrhapontigenin (DOP) against isoflurane
(ISF)-induced neuronal injury in rats. Neuronal injury was induced in pups by exposing them …

Metabolism and Receptor Mechanisms of Niacin Action

SE Boronovskiy, VS Kopylova, YR Nartsissov - Cell and Tissue Biology, 2024 - Springer
The paper discusses the metabolism of niacin, also known as vitamin B3 or PP, and the
mechanisms of its receptor-induced functions in the human body. Niacin exists as several …

OPEN ACCESS EDITED BY

R Rastmanesh, E Gumpricht, F Paul… - … of Chronutrition: A …, 2023 - books.google.com
Methods: After screening, 28 studies were included in this systematic review. Results: In
addition to weight loss, IF could benefit health subjects by strengthening their circadian …

Spinocerebellar Ataxia Type 7: From Mechanistic Pathways to Therapeutic Opportunities

PM Switonski, AR La Spada - Trials for Cerebellar Ataxias: From Cellular …, 2023 - Springer
Abstract Spinocerebellar ataxia type 7 (SCA7) is a cerebellar and retinal neurodegenerative
disease caused by a CAG/polyglutamine (polyQ) expansion mutation in the ataxin-7 …

[PDF][PDF] In silico approach in the development of structural analogues of resveratrol with improved distribution in the central nervous system

D Mitrović, N Pavlović - Kragujevac Journal of Science, 2024 - pdfs.semanticscholar.org
Resveratrol exerts neuroprotective effects that are not only due to antiinflammatory and
antioxidant activity but also by launched biogenesis via sirtuin-1 (SIRT1) protein that protects …

Restoring Homeostasis as a Promising Therapeutic Strategy for Obesity and Sleep Disorders

V Kumar, S Ghosh, PK Mishra, A Aziz, R Mehta… - 2023 - preprints.org
Accumulation of extra fats in the body results in disturbance in homeostasis causing obesity.
The pathophysiology of obesity has been associated with various genetic, epigenetic factors …