[HTML][HTML] SARS-CoV-2 variants, spike mutations and immune escape
Although most mutations in the severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) genome are expected to be either deleterious and swiftly purged or relatively …
CoV-2) genome are expected to be either deleterious and swiftly purged or relatively …
Naturally enhanced neutralizing breadth against SARS-CoV-2 one year after infection
More than one year after its inception, the coronavirus disease 2019 (COVID-19) pandemic
caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) remains difficult …
caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) remains difficult …
Complete map of SARS-CoV-2 RBD mutations that escape the monoclonal antibody LY-CoV555 and its cocktail with LY-CoV016
Monoclonal antibodies and antibody cocktails are a promising therapeutic and prophylaxis
for coronavirus disease 2019 (COVID-19). However, ongoing evolution of severe acute …
for coronavirus disease 2019 (COVID-19). However, ongoing evolution of severe acute …
Antibodies elicited by mRNA-1273 vaccination bind more broadly to the receptor binding domain than do those from SARS-CoV-2 infection
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants
with mutations in key antibody epitopes has raised concerns that antigenic evolution could …
with mutations in key antibody epitopes has raised concerns that antigenic evolution could …
[HTML][HTML] The monoclonal antibody combination REGEN-COV protects against SARS-CoV-2 mutational escape in preclinical and human studies
Monoclonal antibodies against SARS-CoV-2 are a clinically validated therapeutic option
against COVID-19. Because rapidly emerging virus mutants are becoming the next major …
against COVID-19. Because rapidly emerging virus mutants are becoming the next major …
SARS-CoV-2 neutralizing antibodies: Longevity, breadth, and evasion by emerging viral variants
F Tea, A Ospina Stella, A Aggarwal… - PLoS …, 2021 - journals.plos.org
The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) antibody
neutralization response and its evasion by emerging viral variants and variant of concern …
neutralization response and its evasion by emerging viral variants and variant of concern …
Persistent SARS-CoV-2 infection and intra-host evolution in association with advanced HIV infection
While most people effectively clear SARS-CoV-2, there are several reports of prolonged
infection in immunosuppressed individuals. Here we present a case of prolonged infection …
infection in immunosuppressed individuals. Here we present a case of prolonged infection …
Genetic diversity and evolutionary convergence of cryptic SARS-CoV-2 lineages detected via wastewater sequencing
DA Gregory, M Trujillo, C Rushford, A Flury… - PLoS …, 2022 - journals.plos.org
Wastewater-based epidemiology (WBE) is an effective way of tracking the appearance and
spread of SARS-COV-2 lineages through communities. Beginning in early 2021, we …
spread of SARS-COV-2 lineages through communities. Beginning in early 2021, we …
Mutation-specific SARS-CoV-2 PCR screen: rapid and accurate detection of variants of concern and the identification of a newly emerging variant with spike L452R …
H Wang, S Jean, R Eltringham, J Madison… - Journal of clinical …, 2021 - Am Soc Microbiol
The emergence of more transmissible and/or more virulent severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOC) has triggered intensive …
syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOC) has triggered intensive …
Molecular rationale for SARS-CoV-2 spike circulating mutations able to escape bamlanivimab and etesevimab monoclonal antibodies
The purpose of this work is to provide an in silico molecular rationale of the role eventually
played by currently circulating mutations in the receptor binding domain of the SARS-CoV-2 …
played by currently circulating mutations in the receptor binding domain of the SARS-CoV-2 …