Skin aging, cellular senescence and natural polyphenols

E Csekes, L Račková - International journal of molecular sciences, 2021 - mdpi.com
The skin, being the barrier organ of the body, is constitutively exposed to various stimuli
impacting its morphology and function. Senescent cells have been found to accumulate with …

Consequences of COVID-19 for the Pancreas

U Abramczyk, M Nowaczyński, A Słomczyński… - International journal of …, 2022 - mdpi.com
Although coronavirus disease 2019 (COVID-19)-related major health consequences involve
the lungs, a growing body of evidence indicates that COVID-19 is not inert to the pancreas …

Epigenetic underpinnings of inflammation: Connecting the dots between pulmonary diseases, lung cancer and COVID-19

S Ahmad, S Manzoor, S Siddiqui, N Mariappan… - Seminars in cancer …, 2022 - Elsevier
Inflammation is an essential component of several respiratory diseases, such as chronic
obstructive pulmonary disease (COPD), asthma and acute respiratory distress syndrome …

The Impact of Angiotensin-Converting Enzyme 2 (ACE2) Expression Levels in Patients with Comorbidities on COVID-19 Severity: A Comprehensive Review

R Rodrigues, S Costa de Oliveira - Microorganisms, 2021 - mdpi.com
Angiotensin-Converting Enzyme 2 (ACE2) has been proved to be the main host cell receptor
for the binding of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the …

Interplay of opposing effects of the WNT/β-catenin pathway and PPARγ and implications for SARS-CoV2 treatment

A Vallee, Y Lecarpentier, JN Vallee - Frontiers in immunology, 2021 - frontiersin.org
The Coronavirus disease 2019 (COVID-19), caused by the novel coronavirus SARS-CoV-2
(severe acute respiratory syndrome coronavirus 2), has quickly reached pandemic …

Experimental and clinical data analysis for identification of COVID-19 resistant ACE2 mutations

PK Raghav, A Raghav, A Lathwal, A Saxena, Z Mann… - Scientific reports, 2023 - nature.com
The high magnitude zoonotic event has caused by Severe Acute Respitarory Syndrome
CoronaVirus-2 (SARS-CoV-2) is Coronavirus Disease-2019 (COVID-19) epidemics. This …

Molecular mechanisms of COVID-19-induced pulmonary fibrosis and epithelial-mesenchymal transition

P Pi, Z Zeng, L Zeng, B Han, X Bai, S Xu - Frontiers in Pharmacology, 2023 - frontiersin.org
As the outbreak of COVID-19 caused by severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) first broke out in Hubei Province, China, at the end of 2019. It has brought …

CDK4/6 inhibitor palbociclib promotes SARS-CoV-2 cell entry by down-regulating SKP2 dependent ACE2 degradation

Y Xiao, Y Yan, L Chang, H Ji, H Sun, S Song, K Feng… - Antiviral Research, 2023 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19) outbreak has become a global pandemic.
CDK4/6 inhibitor palbociclib was reported to be one of the top-scored repurposed drugs to …

Development and clinical validation of novel 8-gene prognostic signature associated with the proportion of regulatory T cells by weighted gene co-expression network …

J Liu, R Geng, S Yang, F Shao, Z Zhong… - Frontiers in …, 2021 - frontiersin.org
Background Uterine corpus endometrial carcinoma (UCEC) is a gynecological malignant
tumor with low survival rate and poor prognosis. The traditional clinicopathological staging is …

PPAR ligands induce antiviral effects targeting perturbed lipid metabolism during SARS-CoV-2, HCV, and HCMV infection

M Fantacuzzi, R Amoroso, A Ammazzalorso - Biology, 2022 - mdpi.com
Simple Summary The current coronavirus disease 2019 pandemic turned the attention of
researchers to developing novel strategies to counteract virus infections. Despite several …