Long non-coding RNA PVT1 interacts with MYC and its downstream molecules to synergistically promote tumorigenesis

K Jin, S Wang, Y Zhang, M Xia, Y Mo, X Li, G Li… - Cellular and Molecular …, 2019 - Springer
Numerous studies have shown that non-coding RNAs play crucial roles in the development
and progression of various tumor cells. Plasmacytoma variant translocation 1 (PVT1) mainly …

lncRNA PVT1: a novel oncogene in multiple cancers

R Li, X Wang, C Zhu, K Wang - Cellular & molecular biology letters, 2022 - Springer
Long noncoding RNAs are involved in epigenetic gene modification, including binding to the
chromatin rearrangement complex in pre-transcriptional regulation and to gene promoters in …

LncRNA INHEG promotes glioma stem cell maintenance and tumorigenicity through regulating rRNA 2'-O-methylation

L Liu, Z Liu, Q Liu, W Wu, P Lin, X Liu, Y Zhang… - Nature …, 2023 - nature.com
Glioblastoma (GBM) ranks among the most lethal of human cancers, containing glioma stem
cells (GSCs) that display therapeutic resistance. Here, we report that the lncRNA INHEG is …

LncRNA PVT1 regulates atrial fibrosis via miR-128-3p-SP1-TGF-β1-Smad axis in atrial fibrillation

F Cao, Z Li, W Ding, L Yan, Q Zhao - Molecular Medicine, 2019 - Springer
Abstract Background Long non-coding RNAs (lncRNA) plasmacytoma variant translocation
1 (PVT1) has been shown to be associated with liver fibrosis. Nevertheless, the role of PVT1 …

Blocking lncRNA MALAT1/miR-199a/ZHX1 axis inhibits glioblastoma proliferation and progression

K Liao, Y Lin, W Gao, Z Xiao, R Medina… - … Therapy-Nucleic Acids, 2019 - cell.com
Zinc fingers and homeoboxes 1 (ZHX1) is a transcription repressor that has been implicated
in the tumorigenesis and progression of diverse tumors. The functional role and regulating …

Long non-coding RNAs in brain tumors: roles and potential as therapeutic targets

SH Kim, KH Lim, S Yang, JY Joo - Journal of hematology & oncology, 2021 - Springer
Brain tumors are associated with adverse outcomes despite improvements in radiation
therapy, chemotherapy, and photodynamic therapy. However, treatment approaches are …

PVT1 promotes cancer progression via MicroRNAs

W Wang, R Zhou, Y Wu, Y Liu, W Su, W Xiong… - Frontiers in …, 2019 - frontiersin.org
Non-coding RNA (ncRNA) plays a regulatory role in a variety of cellular activities. And long
non-coding RNA (lncRNA) is one of the important kinds of ncRNA. Previous studies have …

Oncogenic role of PVT1 and therapeutic implications

OT Onagoruwa, G Pal, C Ochu, OO Ogunwobi - Frontiers in oncology, 2020 - frontiersin.org
PVT1, a long non-coding RNA has been implicated in a variety of human cancers. Recent
advancements have led to increasing discovery of the critical roles of PVT1 in cancer …

The role of miR-128 in cancer development, prevention, drug resistance, and immunotherapy

HS Budi, LA Younus, MH Lafta, S Parveen… - Frontiers in …, 2023 - frontiersin.org
A growing body of evidence has revealed that microRNA (miRNA) expression is
dysregulated in cancer, and they can act as either oncogenes or suppressors under certain …

A novel lncRNA panel related to ferroptosis, tumor progression, and microenvironment is a robust prognostic indicator for glioma patients

Y He, Y Ye, W Tian, H Qiu - Frontiers in Cell and Developmental …, 2021 - frontiersin.org
Objective: To establish a lncRNA panel related to ferroptosis, tumor progression, and
microenvironment for prognostic estimation in patients with glioma. Methods: LncRNAs …