IBD, including ulcerative colitis and Crohn's disease, is a chronic and debilitating
gastrointestinal disorder that affects millions of people worldwide. Research on IBD has …

Lung cancer is the most common tumor with severe morbidity and high mortality. Increasing
evidence has demonstrated that SNX20 plays crucial roles in the progression of human …

We now have an increased understanding of the genetics, cell biology, and physiology of
electrolyte transport processes in the mammalian intestine, due to the availability of …

Background Colitis-associated cancer (CAC) is one of the prognostic factors in inflammatory
bowel disease (IBD), and prevention of CAC is a critical concern for patients with IBD …

Background: Genetic and other biological factors may lead to differences in disease
behavior among children with inflammatory bowel disease of different races, which may be …

Background The genetic contributions to pediatric onset ulcerative colitis (UC),
characterized by severe disease and extensive colonic involvement, are largely unknown. In …

The purpose of this study was to evaluate genome-wide DNA methylation changes in
intestinal mucosa tissue of adult patients with Crohn's disease comprehensively. DNA …

Background and Aims Associations between diet habits and inflammatory bowel disease
(IBD) have been widely described. Flavonoids are taken with vegetables, fruits, and green …

The mainstay of moderate to severe Crohn's disease (CD), anti-TNF treatment, shows no
clinical benefit in∼ 40% of patients, likely due to incomplete cellular targeting and delayed …

Genome-wide association studies have identified~ 170 loci associated with Crohn's disease
(CD) and defining which genes drive these association signals is a major challenge. The …