COVID-19 vaccines: current and future perspectives

L Soraci, F Lattanzio, G Soraci, ME Gambuzza… - Vaccines, 2022 - mdpi.com
Currently available vaccines against severe acute respiratory syndrome coronavirus-2
(SARS-CoV-2) are highly effective but not able to keep the coronavirus disease 2019 …

Efficacy and safety of a recombinant plant-based adjuvanted Covid-19 vaccine

KJ Hager, G Pérez Marc, P Gobeil… - New England journal …, 2022 - Mass Medical Soc
Abstract Background Coronavirus-like particles (CoVLP) that are produced in plants and
display the prefusion spike glycoprotein of the original strain of severe acute respiratory …

Vaccine development against tuberculosis before and after Covid-19

SHE Kaufmann - Frontiers in Immunology, 2023 - frontiersin.org
Coronavirus disease (Covid-19) has not only shaped awareness of the impact of infectious
diseases on global health. It has also provided instructive lessons for better prevention …

The Third dose of CoronVac vaccination induces broad and potent adaptive immune responses that recognize SARS-CoV-2 Delta and Omicron variants

Y Chen, L Chen, S Yin, Y Tao, L Zhu… - Emerging microbes & …, 2022 - Taylor & Francis
The waning humoral immunity and emerging contagious severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) variants resulted in the necessity of the booster vaccination of …

Safety and immunogenicity of anti-SARS CoV-2 vaccine SOBERANA 02 in homologous or heterologous scheme: Open label phase I and phase IIa clinical trials

M Eugenia-Toledo-Romaní, L Verdecia-Sánchez… - Vaccine, 2022 - Elsevier
Background SOBERANA 02 is a COVID-19 vaccine based on SARS-CoV-2 recombinant
RBD conjugated to tetanus toxoid (TT). SOBERANA Plus antigen is dimeric-RBD. Here we …

Safety and efficacy of combined intramuscular/intranasal RAZI-COV PARS vaccine candidate against SARS-CoV-2: a preclinical study in several animal models

SR Banihashemi, A Es-Haghi… - Frontiers in …, 2022 - frontiersin.org
Several vaccine candidates for COVID-19 have been developed, and few vaccines received
emergency approval with an acceptable level of efficacy and safety. We herein report the …

Exosome-based multivalent vaccine: achieving potent immunization, broadened reactivity, and strong T-cell responses with nanograms of proteins

M Cacciottolo, JB Nice, Y Li, MJ LeClaire… - Microbiology …, 2023 - Am Soc Microbiol
Currently approved vaccines against severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) have focused solely on the spike protein to provide immunity. The first …

SARS-CoV-2 variants offer a second chance to fix vaccine inequities

PJ Hotez - Nature Reviews Microbiology, 2023 - nature.com
Global COVID-19 vaccine equity remains aspirational for much of the world. But the
emergence of rapidly evolving SARS-CoV-2 variants provides new opportunities to correct …

Prospects for developing an hepatitis C virus E1E2‐based nanoparticle vaccine

EA Toth, AK Andrianov… - Reviews in Medical …, 2023 - Wiley Online Library
Globally, more than 58 million people are chronically infected with Hepatitis C virus (HCV)
with 1.5 million new infections occurring each year. An effective vaccine for HCV is therefore …

Recent developments in vaccine design: from live vaccines to recombinant toxin vaccines

S Gupta, S Pellett - Toxins, 2023 - mdpi.com
Vaccines are one of the most effective strategies to prevent pathogen-induced illness in
humans. The earliest vaccines were based on live inoculations with low doses of live or …