Inflammation is one of the well-recognized nontraditional risk factors that contributes to the
excessive cardiovascular mortality in peritoneal dialysis (PD) patients. Serum C-reactive …

During peritoneal dialysis, peritoneal cells are repeatedly exposed to a non-physiological
hypertonic environment with high glucose content and low pH. Current sterile dialysis …

Acidosis commonly exists in the tissue microenvironment of various pathophysiological
conditions such as tumors, inflammation, ischemia, metabolic disease, and respiratory …

Proton-sensing ovarian cancer G-protein coupled receptor (OGR1) plays an important role
in pH homeostasis. Acidosis occurs at sites of intestinal inflammation and can induce …

Absorption of 808 nm laser light by liposomes containing a pH sensitive, near-infrared
croconaine rotaxane dye increases dramatically in weak acid. A stealth liposome …

Acidosis of the tumor microenvironment is a characteristic of solid tumors such as malignant
melanoma. Main causes of the extracellular acidification are metabolic alterations in cancer …

Endoplasmic reticulum (ER) stress and consequent unfolded protein response (UPR) are
involved in a diverse range of pathologies including ischemic diseases, neurodegenerative …

Epithelial-to-mesenchymal transition (EMT) and apoptosis of peritoneal mesothelial cells are
known to be the earliest mechanisms of peritoneal fibrosis in peritoneal dialysis (PD) …

Endoplasmic reticulum (ER) stress and the adaptive response that follows, termed the
unfolded protein response (UPR), are crucial molecular mechanisms to maintain cellular …

Peritoneal mesothelial cells exposed to bioincompatible dialysis fluids contribute to damage
of the peritoneum during chronic dialysis. Inflammatory response triggered in the …