[HTML][HTML] Mucosal and cutaneous human papillomavirus infections and cancer biology

T Gheit - Frontiers in Oncology, 2019 - frontiersin.org
Papillomaviridae is a family of small non-enveloped icosahedral viruses with double-
stranded circular DNA. More than 200 different human papillomaviruses (HPVs) have been …

[HTML][HTML] The role of integration in oncogenic progression of HPV-associated cancers

AA McBride, A Warburton - PLoS pathogens, 2017 - journals.plos.org
Persistent infection with a subset of “high oncogenic risk” human papillomaviruses (HPVs)
can promote the development of cancer. In these cancers, the extrachromosomal viral …

HPV and cancer of the oral cavity

CU Hübbers, B Akgül - Virulence, 2015 - Taylor & Francis
Increased awareness of human papillomavirus (HPV) as an etiological cause of head and
neck squamous cell carcinoma has increased the interest in analysis of distinct oral sub …

Pathogenesis of human papillomavirus‐associated mucosal disease

IJ Groves, N Coleman - The Journal of pathology, 2015 - Wiley Online Library
Human papillomaviruses (HPVs) are a necessary cause of carcinoma of the cervix and other
mucosal epithelia. Key events in high‐risk HPV (HRHPV)‐associated neoplastic …

[HTML][HTML] Analysis of The Cancer Genome Atlas sequencing data reveals novel properties of the human papillomavirus 16 genome in head and neck squamous cell …

TJ Nulton, AL Olex, M Dozmorov, IM Morgan… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Human papillomavirus (HPV) DNA is detected in up to 80% of oropharyngeal carcinomas
(OPC) and this HPV positive disease has reached epidemic proportions. To increase our …

[HTML][HTML] Human papillomaviruses in epigenetic regulations

J Durzynska, K Lesniewicz, E Poreba - Mutation Research/Reviews in …, 2017 - Elsevier
Abstract Human Papillomaviruses (HPVs) are double-stranded DNA viruses, that infect
epithelial cells and are etiologically involved in the development of human cancer. Today …

Genomic characterization of viral integration sites in HPV‐related cancers

C Bodelon, ME Untereiner, MJ Machiela… - … journal of cancer, 2016 - Wiley Online Library
Persistent infection with carcinogenic human papillomaviruses (HPV) causes the majority of
anogenital cancers and a subset of head and neck cancers. The HPV genome is frequently …

Viral load, gene expression and mapping of viral integration sites in HPV16‐associated HNSCC cell lines

NC Olthof, CU Huebbers, J Kolligs… - … journal of cancer, 2015 - Wiley Online Library
HPV‐related HNSCC generally have a better prognosis than HPV‐negative HNSCC.
However, a subgroup of HPV‐positive tumors with poor prognosis has been recognized …

Human Papilloma Virus Specific Immunogenicity and Dysfunction of CD8+ T Cells in Head and Neck Cancer

S Krishna, P Ulrich, E Wilson, F Parikh, P Narang… - Cancer research, 2018 - AACR
Abstract Human papillomavirus subtype 16 (HPV16) is the primary cause of an increasing
number of head and neck squamous cell carcinomas (HNSCC), providing strong rationale …

[HTML][HTML] Molecular mechanisms of human papillomavirus-related carcinogenesis in head and neck cancer

F Faraji, M Zaidi, C Fakhry, DA Gaykalova - Microbes and infection, 2017 - Elsevier
This review examines the general cellular and molecular underpinnings of human
papillomavirus (HPV)-related carcinogenesis in the context of head and neck squamous cell …