Zinc: from biological functions to therapeutic potential

MI Costa, AB Sarmento-Ribeiro… - International Journal of …, 2023 - mdpi.com
The trace element zinc (Zn) displays a wide range of biological functions. Zn ions control
intercellular communication and intracellular events that maintain normal physiological …

The EVER proteins as a natural barrier against papillomaviruses: a new insight into the pathogenesis of human papillomavirus infections

M Lazarczyk, P Cassonnet, C Pons… - Microbiology and …, 2009 - Am Soc Microbiol
Infections by human papillomaviruses (HPVs) are the most frequently occurring sexually
transmitted diseases. The crucial role of genital oncogenic HPV in cervical carcinoma …

Zinc deficiency induces inflammation and apoptosis via oxidative stress in the kidneys of mice

Y Xu, A Li, X Li, X Deng, X Gao - Biological Trace Element Research, 2023 - Springer
Zinc (Zn) is an essential element that regulates not only cellular immunity but also
antioxidant and anti-inflammatory agents. The present study investigated the effect of Zn …

The plasma zinc/serum copper ratio as a biomarker in children with autism spectrum disorders

S Faber, GM Zinn, JC Kern Ii, HM Skip Kingston - Biomarkers, 2009 - Taylor & Francis
The frequency of zinc deficiency, copper toxicity and low zinc/copper in children with autism
spectrum disorders (ASDs) may indicate decrement in metallothionein system functioning. A …

Serum copper and zinc levels in individuals with autism spectrum disorders

S Li, J Wang, G Bjørklund, W Zhao, C Yin - Neuroreport, 2014 - journals.lww.com
Trace elements play a critical role in the pathogenesis of autism spectrum disorders (ASD).
The aim of this study was to investigate the serum levels of zinc (Zn) and copper (Cu) in …

Association between serum copper, zinc, and selenium concentrations and depressive symptoms in the US adult population, NHANES (2011–2016)

D Huang, S Lai, S Zhong, Y Jia - BMC psychiatry, 2023 - Springer
Background Evidence suggests that alterations in serum trace element concentrations are
closely associated with mental illness. However,​ studies on the relationship between …

Zinc homeostasis and immunosenescence

M Maywald, L Rink - Journal of trace elements in medicine and biology, 2015 - Elsevier
For more than 50 years, zinc is known to be an essential trace element, having a regulatory
role in the immune system. Deficiency in zinc thus compromises proper immune function …

Deciphering the antitumoral potential of the bioactive metabolites from medicinal mushroom Inonotus obliquus

Y Zhao, W Zheng - Journal of Ethnopharmacology, 2021 - Elsevier
Ethnopharmacological relevance The crude extracts of the medicinal mushroom Inonotus
obliquus have been used as an effective traditional medicine to treat malicious tumors …

Rebalancing the unbalanced aged immune system–A special focus on zinc

BR Baarz, L Rink - Ageing research reviews, 2022 - Elsevier
Nowadays, aging is understood as a dynamic and multifaceted dysregulation process that
spares almost no human organ or cell. The immune system being among the most affected …

Distinctive modulation of inflammatory and metabolic parameters in relation to zinc nutritional status in adult overweight/obese subjects

L Costarelli, E Muti, M Malavolta, C Cipriano… - The Journal of nutritional …, 2010 - Elsevier
Overweight and obesity are associated with low grade of inflammation and chronic
inflammatory response characterized by abnormal production and activation of some pro …