Skeletal muscle atrophy is prevalent in a myriad of pathological conditions, such as
diabetes, denervation, long-term immobility, malnutrition, sarcopenia, obesity, Alzheimer's …

Background Adiposity has been previously associated with cognitive impairment and
Alzheimer's disease and related disorders (ADRD). Body mass index (BMI) is the most …

Exercise has systemic health benefits in people, in part, through improving whole body
insulin sensitivity. The brain is an insulin-sensitive organ that is often underdiscussed …

Geroscience, an emerging discipline at the intersection of aging and disease, seeks to
understand the relationship between the aging process and pathogenesis of age-related …

The study purpose was to prove the effectiveness of a plyometric jumping jack,
countermovement jump, and tuck jump training in increasing speed, strength, and limb …

African American/Black individuals have been excluded from several lines of prominent
neuroscience research, despite exhibiting disproportionately higher risk factors associated …

Background Disuse atrophy is a frequent cause of muscle atrophy, which can occur in
individuals of any age who have been inactive for a prolonged period or immobilization …

Aging is characterised by the progressive accumulation of cellular dysfunction, stress, and
inflammation. A large body of evidence implicates mitochondrial dysfunction as a cause or …

Background The world's population is aging, but life expectancy has risen more than healthy
life expectancy (HALE). With respect to brain and cognition, the prevalence of …

In the widely accepted «cycle of frailty» concept, individuals can enter the cycle through any
of its five components (inactivity, weight loss, weakness, slowness, and exhaustion), leading …