Implications of macrophage polarization in autoimmunity

SC Funes, M Rios, J Escobar‐Vera, AM Kalergis - Immunology, 2018 - Wiley Online Library
Macrophages are extremely heterogeneous and plastic cells with an important role not only
in physiological conditions, but also during inflammation (both for initiation and resolution) …

Fluorescent probe strategy for live cell distinction

X Liu, YT Chang - Chemical Society Reviews, 2022 - pubs.rsc.org
Live cell discrimination is the first and essential step to understand complex biosystems.
Conventional cell discrimination involving various antibodies relies on selective surface …

Theranostic fluorescent probes

A Sharma, P Verwilst, M Li, D Ma, N Singh… - Chemical …, 2024 - ACS Publications
The ability to gain spatiotemporal information, and in some cases achieve spatiotemporal
control, in the context of drug delivery makes theranostic fluorescent probes an attractive …

A functional chemiluminescent probe for in vivo imaging of natural killer cell activity against tumours

JI Scott, S Gutkin, O Green… - Angewandte Chemie …, 2021 - Wiley Online Library
Natural killer (NK) cells are immune cells that can kill certain types of cancer cells. Adoptive
transfer of NK cells represents a promising immunotherapy for malignant tumours; however …

Fluorogenic reaction-based prodrug conjugates as targeted cancer theranostics

MH Lee, A Sharma, MJ Chang, J Lee, S Son… - Chemical Society …, 2018 - pubs.rsc.org
Theranostic systems are receiving ever-increasing attention due to their potential
therapeutic utility, imaging enhancement capability, and promise for advancing the field of …

Near-infrared fluorescent probes for the detection of cancer-associated proteases

JI Scott, Q Deng, M Vendrell - ACS chemical biology, 2021 - ACS Publications
Proteases are enzymes capable of catalyzing protein breakdown, which is critical across
many biological processes. There are several families of proteases, each of which perform …

[HTML][HTML] M2 macrophages in kidney disease: biology, therapies, and perspectives

T Chen, Q Cao, Y Wang, DCH Harris - Kidney international, 2019 - Elsevier
Tissue macrophages are crucial players in homeostasis, inflammation, and immunity. They
are characterized by heterogeneity and plasticity, due to which they display a continuum of …

Chemodivergent manganese-catalyzed C–H activation: modular synthesis of fluorogenic probes

N Kaplaneris, J Son, L Mendive-Tapia, A Kopp… - Nature …, 2021 - nature.com
Bioorthogonal late-stage diversification of amino acids and peptides bears enormous
potential for drug discovery and molecular imaging. Despite major accomplishments, these …

SCOTfluors: small, conjugatable, orthogonal, and tunable fluorophores for in vivo imaging of cell metabolism

S Benson, A Fernandez, ND Barth… - Angewandte …, 2019 - Wiley Online Library
The transport and trafficking of metabolites are critical for the correct functioning of live cells.
However, in situ metabolic imaging studies are hampered by the lack of fluorescent …

Miniaturized chemical tags for optical imaging

S Benson, F De Moliner, W Tipping… - Angewandte Chemie …, 2022 - Wiley Online Library
Recent advances in optical bioimaging have prompted the need for minimal chemical
reporters that can retain the molecular recognition properties and activity profiles of …