Chronic kidney disease (CKD) is a severe condition and a significant public health issue
worldwide, carrying the burden of an increased risk of cardiovascular events and mortality …

Inflammasomes are thought to be important mediators of host defense against microbial
pathogens and maintenance of gastrointestinal tract homeostasis. They can modulate …

Neurodegenerative diseases are neurological disorders that become more prevalent with
age, usually caused by damage or loss of neurons or their myelin sheaths, such as …

Obesity is an important risk factor and common comorbidity of childhood asthma.
Simultaneously, obesity-related asthma, a distinct asthma phenotype, has attracted …

Type 2 diabetes mellitus (T2DM) poses a significant risk to human health. Previous research
demonstrated that Inonotus obliquus possesses good hypolipidemic, anti-inflammatory, and …

The role of gut dysbiosis in depression is well established. However, recent studies have
shown that gut microbiota is regulated by intestinal epithelial cell (IEC) mitochondria, which …

Abstract NLRP3 (NOD-, LRR-and pyrin domain-containing protein 3), a member of the
nucleotide-binding domain (NOD) and leucine-rich repeat sequence (LRR) protein (NLR) …

Intestinal microbiota plays an indispensable role in the host's innate immune system, which
may be related to the occurrence of many autoimmune diseases. Hashimoto thyroiditis (HT) …

The present study aimed to investigate the effect of photoperiod on the intestinal
inflammation and gut microbiota. A total of 96 broiler chickens were divided into 2 groups …

Multiple sclerosis (MS) is a complex autoimmune disorder that impacts the central nervous
system (CNS), resulting in inflammation, demyelination, and neurodegeneration. The NOD …