Children born small for gestational age: differential diagnosis, molecular genetic evaluation, and implications

MJJ Finken, M van der Steen, CCJ Smeets… - Endocrine …, 2018 - academic.oup.com
Children born small for gestational age (SGA), defined as a birth weight and/or length
below− 2 SD score (SDS), comprise a heterogeneous group. The causes of SGA are …

International consensus guideline on small for gestational age: etiology and management from infancy to early adulthood

ACS Hokken-Koelega, M van der Steen… - Endocrine …, 2023 - academic.oup.com
Abstract This International Consensus Guideline was developed by experts in the field of
small for gestational age (SGA) of 10 pediatric endocrine societies worldwide. A consensus …

Personalized approach to growth hormone treatment: clinical use of growth prediction models

JM Wit, MB Ranke, K Albertsson-Wikland… - Hormone research in …, 2013 - karger.com
The goal of growth hormone (GH) treatment in a short child is to attain a fast catch-up growth
toward the target height (TH) standard deviation score (SDS), followed by a maintenance …

[HTML][HTML] Current insights into the role of the growth hormone-insulin-like growth factor system in short children born small for gestational age

JS Renes, J Van Doorn… - Hormone research in …, 2019 - karger.com
Background: The reason for the insufficient catch-up growth seen in 10% of children born
small for gestational age (SGA) is poorly understood. Disturbances in the growth hormone …

Predicting growth in response to growth hormone treatment

MB Ranke, A Lindberg - Growth Hormone & IGF Research, 2009 - Elsevier
The use of growth hormone (GH) to treat children who have disturbances of growth is
complicated by variability both within and across diagnostic groups, and at the start of and …

Towards optimal treatment with growth hormone in short children and adolescents: evidence and theses

MB Ranke, A Lindberg, PE Mullis, ME Geffner… - Hormone research in …, 2013 - karger.com
Abstract Treatment with growth hormone (GH) has become standard practice for
replacement in GH-deficient children or pharmacotherapy in a variety of disorders with short …

Growth hormone (GH) dosing during catch-up growth guided by individual responsiveness decreases growth response variability in prepubertal children with GH …

B Kristrom, AS Aronson, J Dahlgren… - The Journal of …, 2009 - academic.oup.com
Context: Weight-based GH dosing results in a wide variation in growth response in children
with GH deficiency (GHD) or idiopathic short stature (ISS). Objective: The hypothesis tested …

Height at start, first-year growth response and cause of shortness at birth are major determinants of adult height outcomes of short children born small for gestational …

MB Ranke, A Lindberg… - Hormone research in …, 2010 - karger.com
Abstract Background/Aims: There is limited information about adult height (AH) outcomes
and the factors influencing outcomes of growth hormone (GH) therapy in short children born …

[PDF][PDF] Achieving optimal short-and long-term responses to paediatric growth hormone therapy

JM Wit, A Deeb, B Bin-Abbas… - Journal of Clinical …, 2019 - jag.journalagent.com
It is over sixty years since the first administration of human growth hormone (GH) to children
with GH deficiency, and over thirty years since recombinant human GH has been available …

Growth and metabolism in children born small for gestational age

M van der Steen… - … and Metabolism Clinics, 2016 - endo.theclinics.com
Growth and development are important and sensitive parameters of health and disease. The
most important measure of growth is body length. Several factors influence postnatal growth …