Autism spectrum disorder (ASD) is often grouped with other brain-related phenotypes into a
broader category of neurodevelopmental disorders (NDDs). In clinical practice, providers …

Recent advances in genomics have revealed a wide spectrum of genetic variants
associated with neurodevelopmental disorders at an unprecedented scale. An increasing …

Alternative RNA splicing increases transcript diversity in different cell types and under
varying conditions. It is executed with the help of RNA splicing regulators (RSRs), which are …

Recent clinical and preclinical evidence points towards empathogenic and prosocial effects
elicited by psychedelic compounds, notably the serotonin 5-HT 2A agonists lysergic acid …

Regulation of translation during human development is poorly understood, and its
dysregulation is associated with Rett syndrome (RTT). To discover shifts in mRNA ribosomal …

NMDA receptors (NMDARs), a prominent subtype of glutamatergic receptors, are implicated
in the pathogenesis and development of neuropsychiatric disorders such as epilepsy …

Synapses are involved in the communication of information from one neuron to another.
However, a systematic analysis of synapse density in the neocortex from a diversity of …

The emergence of novel sequencing technologies has greatly improved the identification of
structural variation, revealing that a human genome harbors tens of thousands of structural …

Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder caused by
genetic or environmental perturbations during early development. Diagnoses are dependent …

Neurodevelopmental disorders (NDDs) are a heterogeneous class of brain diseases, with a
complex genetic basis estimated to account for up to 50% of cases. Nevertheless, genetic …