Higher mortality of COVID-19 in males: sex differences in immune response and cardiovascular comorbidities

LA Bienvenu, J Noonan, X Wang… - Cardiovascular …, 2020 - academic.oup.com
The high mortality rate of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)
infection is a critical concern of the coronavirus disease 2019 (COVID-19) pandemic …

Aging & COVID-19 susceptibility, disease severity, and clinical outcomes: The role of entangled risk factors

M Farshbafnadi, SK Zonouzi, M Sabahi… - Experimental …, 2021 - Elsevier
Abstract The emergence of Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-CoV-
2) in late 2019 has been associated with a high rate of mortality and morbidity. It has been …

[HTML][HTML] Does gender influence clinical expression and disease outcomes in COVID-19? A systematic review and meta-analysis

A Ortolan, M Lorenzin, M Felicetti, A Doria… - International Journal of …, 2020 - Elsevier
Background Severe acute respiratory syndrome coronavirus-2 (SARS-CoV2) was
characterized at the end of 2019, and soon spread around the world, generating a …

COVID-19 and the endocrine system: a comprehensive review on the theme

G Lisco, A De Tullio, A Stragapede… - Journal of clinical …, 2021 - mdpi.com
Background and aim. The review aimed to summarize advances in the topic of endocrine
diseases and coronavirus disease 2019 (COVID-19). Methods. Scientific and institutional …

Sex‐related differences in COVID‐19 lethality

C Penna, V Mercurio, CG Tocchetti… - British journal of …, 2020 - Wiley Online Library
Many countries have been affected by the worldwide outbreak of COVID‐19. Among
Western countries, Italy has been particularly hit at the beginning of the pandemic …

Impact of the SARS‐CoV‐2 virus on male reproductive health

DE Nassau, JC Best, E Kresch, DC Gonzalez… - BJU …, 2022 - Wiley Online Library
The coronavirus 2019 (COVID‐19) pandemic caused by the novel severe acute respiratory
syndrome coronavirus 2 (SARS‐CoV‐2) has led to more than 160 million infections and 3.5 …

An insight into the sex differences in COVID-19 patients: what are the possible causes?

PM Dana, F Sadoughi, J Hallajzadeh… - … and disaster medicine, 2020 - cambridge.org
Studies have reported a sex bias in case fatalities of COVID-19 patients. Moreover, it is
observed that men have a higher risk of developing a severe form of the disease compared …

Potential influence of menstrual status and sex hormones on female severe acute respiratory syndrome coronavirus 2 infection: a cross-sectional multicenter study in …

T Ding, J Zhang, T Wang, P Cui, Z Chen… - Clinical Infectious …, 2021 - academic.oup.com
Background Recent studies have indicated that females with coronavirus disease 2019
(COVID-19) have a lower morbidity, severe case rate, and mortality and better outcome than …

Inhibition of SARS-CoV-2 entry through the ACE2/TMPRSS2 pathway: a promising approach for uncovering early COVID-19 drug therapies

G Ragia, VG Manolopoulos - European journal of clinical pharmacology, 2020 - Springer
Aim The COVID-19 pandemic caused by infection with the novel coronavirus SARS-CoV-2
is urging the scientific community worldwide to intense efforts for identifying and developing …

Genome-wide association study of estradiol levels and the causal effect of estradiol on bone mineral density

D Schmitz, WE Ek, E Berggren… - The Journal of …, 2021 - academic.oup.com
Context Estradiol is the primary female sex hormone and plays an important role for skeletal
health in both sexes. Several enzymes are involved in estradiol metabolism, but few …