Alzheimer's disease (AD) is one of the most common neurodegenerative diseases. Its major
pathological hallmarks, neurofibrillary tangles (NFT), and amyloid-β plaques can result from …

Alzheimer's disease (AD) should be regarded as a degenerative metabolic disease caused
by brain insulin resistance and deficiency, and overlapping with the molecular, biochemical …

Progress toward the development of efficacious therapies for Alzheimer's disease (AD) is
halted by a lack of understanding early underlying pathological mechanisms. Systems …

Alzheimer's disease [AD] is the most common cause of dementia in North America. Despite
30+ years of intense investigation, the field lacks consensus regarding the etiology and …

Obesity is a major public health problem affecting overall physical and emotional well-being.
Despite compelling data suggesting an association between obesity and cognitive …

Plant-derived polyphenols are increasingly receiving attention as dietary supplements for
the homeostatic management of inflammation, to support detoxification, and for anticancer …

Berries contain vitamin C and are also a rich source of phytochemicals, especially
anthocyanins which occur along with other classes of phenolic compounds, including …

In recent years there has been increased interest in whether vascular disease contributes to
Alzheimer's disease (AD). This review considers how modifiable risk factors such as …

The integrity of the vascular system is essential for the efficient functioning of the brain.
Aging-related structural and functional disturbances in the macro-or microcirculation of the …

Alzheimer's disease (AD) is a chronic neurodegenerative disorder, in which multiple risk
factors converge. Despite the complexity of the etiology of the disease, synaptic failure is the …