Interactions between microbiota and host skin have an important impact on cutaneous
immunity and inflammation. In this issue of Cell Host & Microbe, Cha et al. report that skin …

Diabetes mellitus (DM) is accompanied by a series of macrovascular and microvascular
injuries. Critical limb ischemia is the most severe manifestation of peripheral artery disease …

Summary paragraph The host-microbiota relationship has evolved to shape mammalian
processes, including immunity, metabolism, and development–. Host phenotypes change in …

Abstract Interleukin (IL)-22 is produced from immune cells such as T helper (Th) 22 cells,
Th17/22 cells, and group 3 innate lymphoid cells. IL-22 signals via the IL-22 receptor 1 (IL …

Objectives To investigate the characteristics of the skin microbiome in severe afatinib-
induced skin toxicity. Methods Body site-matched skin surface samples were collected from …

The skin barrier is critical in ensuring homeostasis, yet factors influencing its development,
repair, and maintenance are ill-defined. In this issue of Cell Host & Microbe, Uberoi et al …

Atopic dermatitis (AD) is the most common inflammatory skin disease worldwide. It is a
chronic, relapsing and pruritic skin disorder which results from epidermal barrier …

Background Tryptophan metabolism dysregulation has been observed in vitiligo. However,
drawing a mechanistic linkage between this metabolic disturbance and vitiligo pathogenesis …

Vitiligo is an autoimmune skin depigmentation disease characterized by CD8+ T-cell-
mediated loss-of-function melanocytes. The role of autoimmunity in the pathogenesis of …

Background The human skin microbiome and lipidome are essential for skin homeostasis
and barrier function, and have become a focus in both dermatological and cosmetic fields …