P Sahoo, X Yang, D Abler… - Journal of the …, 2020 - royalsocietypublishing.org
Chimeric antigen receptor (CAR) T-cell therapy has shown promise in the treatment of haematological cancers and is currently being investigated for solid tumours, including high …
D Hardiansyah, CM Ng - Clinical and translational science, 2019 - Wiley Online Library
Chimeric antigen receptor T‐cell (CART) therapy is a new and promising cancer therapy. However, severe toxicity due to cytokine release syndrome (CRS) in CART‐treated patients …
K Owens, I Bozic - Bulletin of Mathematical Biology, 2021 - Springer
Abstract The Federal Drug Administration approved the first Chimeric Antigen Receptor T- cell (CAR T-cell) therapies for the treatment of several blood cancers in 2017, and efforts are …
Bispecific T-cell engaging therapies harness the immune system to elicit an effective anticancer response. Modulating the immune activation avoiding potential adverse effects …
I Kareva, F Berezovskaya, G Karev - bioRxiv, 2022 - ncbi.nlm.nih.gov
Cytokine storm is a life-threatening inflammatory response that is characterized by hyperactivation of the immune system, and which can be caused by various therapies …
Chimeric antigen receptor (CAR) T-cell based immunotherapy has shown its potential in treating blood cancers, and its application to solid tumors is currently being extensively …
H Cho, Z Wang, D Levy - Journal of Theoretical Biology, 2020 - Elsevier
Adoptive T cell based immunotherapy is gaining significant traction in cancer treatment. Despite its limited efficacy so far in treating solid tumors compared to hematologic cancers …
I Kareva, JL Gevertz - Mathematics of Control, Signals, and Systems, 2024 - Springer
Cytokine storm is a life-threatening inflammatory response characterized by hyperactivation of the immune system. It can be caused by various therapies, auto-immune conditions, or …
НЛ Григоренко, ЕН Хайлов, ЭВ Григорьева… - … и механики УрО РАН, 2021 - mathnet.ru
Рассматривается управляемая математическая модель лечения лейкемии, в основе которой лежит трехмерная модель хищник жертва Лотки Вольтерры. Эта модель …