Ulcerative colitis (UC) specifically affects the colon and rectum through multifactorial
mechanisms associated with genetic alterations, environmental factors, microbiota, and …

Defining the etiology of inflammatory bowel disease (IBD) continues to elude researchers, in
part due to the possibility that there may be different triggers for a spectrum of disease …

Inflammatory bowel diseases (IBDs) are chronic disorders of the gastrointestinal tract with
the following two subtypes: Crohn's disease (CD) and ulcerative colitis (UC). To date, most …

Inflammatory bowel disease (IBD) results from a complex series of interactions between
susceptibility genes, the environment, and the immune system. Recently, some studies …

Epidemiological and clinical studies have suggested that the pathogenesis of inflammatory
bowel disease (IBD) is strongly influenced by genetic predisposition. Beyond the limitations …

Background and aims Psychologic stress can affect the pathogenesis of inflammatory bowel
disease (IBD), but the precise contribution of psychologic stress to IBD remains unclear. We …

Background There is growing evidence to demonstrate that the epigenetic regulation of
immune characteristics, especially for N6-methyladenosine (m6A) RNA methylation …

Aberrant tumour necrosis factor (TNF) signalling is a hallmark of many inflammatory
diseases including rheumatoid arthritis (RA), irritable bowel disease and lupus. Maladaptive …

Induction of vast transcriptional programs is a central event of innate host responses to viral
infections. Here we report a transcriptional program with potent antiviral activity, driven by …

BACKGROUND. Morphological patterns of Paneth cells are a prognostic biomarker in
Western Crohn's disease (CD) patients, and are associated with autophagy-associated …